2017
Partnering with Psychiatry to Close the Education Gap: An Approach to the Addiction Epidemic
Tetrault JM, Petrakis IL. Partnering with Psychiatry to Close the Education Gap: An Approach to the Addiction Epidemic. Journal Of General Internal Medicine 2017, 32: 1387-1389. PMID: 28766126, PMCID: PMC5698217, DOI: 10.1007/s11606-017-4140-9.Peer-Reviewed Original ResearchMeSH KeywordsBehavior, AddictiveClinical CompetenceCurriculumEducation, MedicalHumansInternal MedicinePsychiatrySubstance-Related DisordersUnited States
2001
Contingency Management Interventions: From Research to Practice
Petry N, Petrakis I, Trevisan L, Wiredu G, Boutros N, Martin B, Kosten T. Contingency Management Interventions: From Research to Practice. American Journal Of Psychiatry 2001, 158: 694-702. PMID: 11329388, DOI: 10.1176/appi.ajp.158.5.694.Peer-Reviewed Original Research
1999
Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients
Krystal J, D'Souza D, Madonick S, Petrakis I. Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients. Schizophrenia Research 1999, 35: s35-s49. PMID: 10190224, DOI: 10.1016/s0920-9964(98)00162-5.Peer-Reviewed Original ResearchConceptsSchizophrenic patientsSubstance abuseTerms of rehospitalizationComorbid substance abuseExacerbation of symptomsHealth care expensesSelf-medication hypothesisBetter prognosisMedical illnessPharmacotherapeutic approachesRational pharmacotherapyNonschizophrenic populationsPatientsVocational functionIllicit substancesCare expensesAbuseVulnerability hypothesisRehospitalizationExacerbationMedicationsPharmacotherapyPrognosisPsychostimulantsIllness
1997
Effect of alpha-methyl-para-tyrosine on response to cocaine challenge
Stine S, Krystal J, Petrakis I, Jatlow P, Heninger G, Kosten T, Chamey D. Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biological Psychiatry 1997, 42: 181-190. PMID: 9232210, DOI: 10.1016/s0006-3223(96)00331-9.Peer-Reviewed Original ResearchConceptsDopamine metabolite homovanillic acidCocaine-induced euphoriaNorepinephrine metabolite 3Placebo-controlled studyBlood pressure responseMetabolite homovanillic acidReduced plasma levelsTyrosine hydroxylase inhibitorSerum cocaine levelsTuberoinfundibular dopamine systemAMPT pretreatmentAcute reductionIntranasal administrationPara-tyrosinePlasma levelsProlactin levelsCocaine challengeHomovanillic acidCatecholamine synthesisHeart rateHydroxylase inhibitorAlpha-methylDopamine systemCocaine levelsTherapeutic potential
1995
Fluoxetine Treatment for Dually Diagnosed Methadone Maintained Opioid Addicts:
Petrakis I, Carroll K, Gordon L, Cushing G, Rounsaville B. Fluoxetine Treatment for Dually Diagnosed Methadone Maintained Opioid Addicts:. Journal Of Addictive Diseases 1995, 13: 25-32. PMID: 7734457, DOI: 10.1300/j069v13n03_03.Peer-Reviewed Original Research
1992
Adjunctive desipramine in the treatment of cocaine abusing schizophrenics.
Ziedonis D, Richardson T, Lee E, Petrakis I, Kosten T. Adjunctive desipramine in the treatment of cocaine abusing schizophrenics. Psychopharmacology Bulletin 1992, 28: 309-14. PMID: 1480735.Peer-Reviewed Original ResearchMeSH KeywordsAdultCocaineDesipramineFemaleHumansMaleSchizophreniaSchizophrenic PsychologySubstance-Related DisordersConceptsAntipsychotic agentsSchizophrenic patientsOpen-label outpatient studySubstance abuse relapse preventionTreatment programDual diagnosis treatment programOnly antipsychotic agentTreatment of cocaineCocaine-positive urinesLifetime prevalence ratesRelapse prevention programAdjunctive pharmacotherapyOutpatient studyPrevalence ratesPsychiatric symptomsPatientsCocaine abuseRelapse preventionPrevention programsCocaine usageDMI groupPharmacotherapyDesipramineSymptomsAgents
1991
Bupropion Reduces Cocaine Abuse in Methadone-Maintained Patients
Margolin A, Kosten T, Petrakis I, Avants S, Kosten T. Bupropion Reduces Cocaine Abuse in Methadone-Maintained Patients. JAMA Psychiatry 1991, 48: 87-87. PMID: 1898631, DOI: 10.1001/archpsyc.1991.01810250089015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive AgentsBupropionCocaineCombined Modality TherapyDrug Therapy, CombinationFemaleHumansMaleMethadonePilot ProjectsPropiophenonesPsychotherapySubstance-Related Disorders
1990
An open pilot study of bupropion and psychotherapy for the treatment of cocaine abuse in methadone-maintained patients.
Margolin A, Kosten T, Petrakis I, Avants S, Kosten T. An open pilot study of bupropion and psychotherapy for the treatment of cocaine abuse in methadone-maintained patients. NIDA Research Monograph 1990, 105: 367-8. PMID: 1908556.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsBupropionCocaineHumansMethadoneOpioid-Related DisordersPropiophenonesPsychotherapySubstance-Related Disorders