Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis
Hicks CW, Canner JK, Arhuidese I, Glebova NO, Schneider E, Qazi U, Perler B, Malas MB. Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis. Journal Of Vascular Surgery 2014, 60: 1585-1592. PMID: 25238724, DOI: 10.1016/j.jvs.2014.08.056.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArea Under CurveAsymptomatic DiseasesBlood Flow VelocityCarotid Artery, CommonCarotid Artery, InternalCarotid StenosisChi-Square DistributionDecision Support TechniquesDisease ProgressionFemaleHumansMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProportional Hazards ModelsRegional Blood FlowRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsUltrasonography, Doppler, DuplexConceptsAsymptomatic carotid artery stenosisICA/CCA ratioCarotid artery stenosisInternal carotid arteryDisease progressionEnd-diastolic velocityPeak systolic velocityRisk prediction modelCCA ratioArtery stenosisSystolic velocityRisk factorsInitial peak systolic velocityProportional hazards regression modelsHigh-risk patientsRisk of progressionRisk-stratify patientsHazards regression modelsSignificant independent predictorsICA/CCACharacteristic curve analysisClinical prediction modelCarotid artery ratioIndependent predictorsDuplex imagingRisk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy
Hicks C, Talbott K, Canner J, Qazi U, Arhuidese I, Glebova N, Freischlag J, Perler B, Malas M. Risk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy. Annals Of Vascular Surgery 2014, 29: 1-8. PMID: 24530720, DOI: 10.1016/j.avsg.2014.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyAsymptomatic DiseasesBaltimoreCarotid StenosisChi-Square DistributionDisease ProgressionDrug Therapy, CombinationEndarterectomy, CarotidFemaleHumansIncidenceIschemic Attack, TransientLinear ModelsMaleMultivariate AnalysisPlatelet Aggregation InhibitorsPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexSmokingStentsStrokeTertiary Care CentersTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexConceptsProgression to severe stenosisAsymptomatic carotid artery stenosisDual antiplatelet therapyCarotid artery stenosisDisease progressionRisk factorsSevere stenosisIncidence of symptomsAntiplatelet therapyArtery stenosisPatient populationMean follow-up timeRisk of disease progressionSevere diseaseCox proportional hazards regression modelsRisk of progressionProportional hazards regression modelsFollow-up timeCarotid artery duplexAll-cause mortalityHazards regression modelsImproved medical therapyTransient ischemic attackTobacco useAsymptomatic carotid disease