2023
Clinical presentation of group B Streptococcus-infected diabetic foot ulcers
Waldman O, Dexter B, Sulovari A, Oh I. Clinical presentation of group B Streptococcus-infected diabetic foot ulcers. Journal Of Wound Care 2023, 32: s19-s25. PMID: 37405964, DOI: 10.12968/jowc.2023.32.sup7.s19.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes MellitusDiabetic FootHemoglobinsHumansRetrospective StudiesStreptococcusWound HealingConceptsDiabetic foot ulcersFoot ulcersBlack patientsRecurrent infectionsElevated hemoglobin A1cIntra-operative culturesHemoglobin A1c levelsInitial laboratory valuesSoft tissue infectionsDFU infectionsDFU patientsInitial surgeryOrthopaedic FootAggressive treatmentClinical characteristicsGBS infectionA1c levelsHemoglobin A1cTissue infectionsClinical outcomesClinical presentationInfected boneAppropriate treatmentGroup BLaboratory values
2020
Intraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis
Brodell JD, Kozakiewicz LN, Hoffman SL, Oh I. Intraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis. Foot & Ankle International 2020, 42: 356-362. PMID: 33185116, DOI: 10.1177/1071100720962480.Peer-Reviewed Original ResearchConceptsDiabetic heel ulcersVancomycin powder applicationTotal calcanectomyVancomycin powderCalcaneal osteomyelitisHeel ulcersClinical outcomesRetrospective case-control studyLimb salvage rateOverall healing rateImproved clinical outcomesCase-control studyLocal tissue irritationMultidrug-resistant bacteriaVancomycin cohortWound complicationsClinical characteristicsOperative complicationsUlcer surgeryDiabetic patientsRevision amputationSalvage rateKnee amputationClinical benefitUnderwent revisionChopart Amputation: Questioning the Clinical Efficacy of a Long-standing Surgical Option for Diabetic Foot Infection.
Brodell JD, Ayers BC, Baumhauer JF, DiGiovanni BF, Flemister AS, Ketz JP, Oh I. Chopart Amputation: Questioning the Clinical Efficacy of a Long-standing Surgical Option for Diabetic Foot Infection. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 684-691. PMID: 32769724, DOI: 10.5435/jaaos-d-19-00757.Peer-Reviewed Original ResearchConceptsBaseline physical functionPROMIS Physical FunctionDiabetic foot infectionsPostoperative wound complicationsChopart amputationRevision amputationFoot infectionsWound complicationsPhysical functionWound healingOutcomes Measurement Information System (PROMIS) instrumentsPROMIS physical function scoresPhysical function scoresPatient-reported outcomesJudicious patient selectionExtent of infectionPostoperative complicationsTotal patientsCase seriesClinical outcomesKnee amputationPain interferencePatient selectionSurgical optionsTendon transfer
2019
Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing
Nichols AEC, Oh I, Loiselle AE. Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing. Journal Of Orthopaedic Research® 2019, 38: 13-22. PMID: 31166037, PMCID: PMC6893090, DOI: 10.1002/jor.24388.Peer-Reviewed Original ResearchConceptsTendon healingTendon functionType II diabetes mellitusPro-inflammatory environmentPre-clinical modelsNovel therapeutic strategiesPotential treatment approachRisk of ruptureHealth care challengesDiabetic tendinopathyDiabetes mellitusDiabetic patientsChronic tendinopathyAcute traumaTendon tearsImpaired restorationPathological progressionTendon repairTherapeutic strategiesTreatment approachesTendon structureUS populationCare challengesNative tendon structureHealingEvidence of differential microbiomes in healing versus non‐healing diabetic foot ulcers prior to and following foot salvage therapy
MacDonald A, Brodell JD, Daiss JL, Schwarz EM, Oh I. Evidence of differential microbiomes in healing versus non‐healing diabetic foot ulcers prior to and following foot salvage therapy. Journal Of Orthopaedic Research® 2019, 37: 1596-1603. PMID: 30908702, PMCID: PMC6659747, DOI: 10.1002/jor.24279.Peer-Reviewed Original ResearchConceptsSalvage therapyQuantitative polymerase chain reactionClinical outcomesClinical toolErythrocyte sedimentation rateFurther surgical interventionC-reactive proteinLower extremity amputationDiabetic foot ulcersEventual clinical outcomeImportant prognostic informationImportant clinical toolDFU patientsFoot salvageFoot ulcersDiabetic footExtremity amputationSurgical interventionPatient counselingAntibiotic treatmentPolymerase chain reactionPrognostic informationClinical signsMicrobiome analysisClinical significance