Distinct vasculotropic versus osteotropic features of S. agalactiae versus S. aureus implant‐associated bone infection in mice
Masters EA, Hao SP, Kenney HM, Morita Y, Galloway CA, de Mesy Bentley K, Ricciardi BF, Boyce BF, Schwarz EM, Oh I. Distinct vasculotropic versus osteotropic features of S. agalactiae versus S. aureus implant‐associated bone infection in mice. Journal Of Orthopaedic Research® 2020, 39: 389-401. PMID: 33336806, PMCID: PMC7882123, DOI: 10.1002/jor.24962.Peer-Reviewed Original ResearchConceptsS. aureus osteomyelitisBone infectionS. agalactiaeAnimal modelsS. aureus bone infectionImplant looseningSoft tissueImplant-associated osteomyelitisQuantitative animal modelCortical boneAdjacent soft tissuesGroup B streptococciS. aureusSeptic implant looseningS. agalactiae infectionAssessment of miceS. aureus virulenceGreater body weightDevastating complicationClinical featuresAbscess formationLocal inflammationAggressive osteolysisLess osteolysisPreclinical modelsGroup B Streptococcus Infected Tenosynovitis in Diabetic Foot Ulcers
Waldman O, Sajda T, Oh I, Sulovari A. Group B Streptococcus Infected Tenosynovitis in Diabetic Foot Ulcers. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00483. PMCID: PMC8702881, DOI: 10.1177/2473011420s00483.Peer-Reviewed Original ResearchDiabetic foot ulcersPost-operative complicationsDFU patientsGBS patientsUnplanned readmissionInflammatory markersRay amputationAcute ulcersSurgical treatmentClinical outcomesFoot ulcersRepeat operationSevere soft tissue inflammationInfected diabetic foot ulcersSevere soft tissue damageElevated inflammatory markersHigh inflammatory markersAggressive surgical treatmentSoft tissue inflammationPost-surgical complicationsOrthopaedic surgeon's practiceGroup B streptococciSoft tissue damageBlood glucose valuesFrequent wound complications