Role of pregabalin in treatment of oxaliplatin-induced sensory neuropathy.
Saif MW, Syrigos K, Kaley K, Isufi I. Role of pregabalin in treatment of oxaliplatin-induced sensory neuropathy. Anticancer Research 2010, 30: 2927-33. PMID: 20683034.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsCapecitabineDeoxycytidineDose-Response Relationship, DrugEpirubicinFemaleFluorouracilGamma-Aminobutyric AcidGastrointestinal NeoplasmsGemcitabineHumansMaleMiddle AgedNeurotoxicity SyndromesOrganoplatinum CompoundsOxaliplatinPregabalinConceptsSensory neuropathyTarget doseLow dosesDose-related side effectsEfficacy of pregabalinOxaliplatin-induced neurotoxicityRole of pregabalinMajority of patientsGastrointestinal cancer patientsOnset of benefitGastrointestinal malignanciesHead trialsNeurological symptomsOxaliplatin useCancer patientsSide effectsPregabalinGrade 2PatientsNeuropathyNeurotoxicityDoseDosesEfficacyTreatment