Treatment Intensity and Outcomes in Elderly Patients with DLBCL Receiving First Line Therapy
Bair S, Narkhede M, Frosch Z, Chong E, Ermann D, Isufi I, Awan F, Chavez J, Bosma G, Abbott D. Treatment Intensity and Outcomes in Elderly Patients with DLBCL Receiving First Line Therapy. Blood 2023, 142: 68. DOI: 10.1182/blood-2023-187113.Peer-Reviewed Original ResearchReal-world progression-free survivalReal-world overall survivalMultivariate Cox regression analysisR-CHOPAlternative regimensAge 70Partial responseTreatment intensityComplete responseMedian ageElderly ptsMedian Charlson Comorbidity Index scoreMedian real-world overall survivalCharlson Comorbidity Index scoreHigh-risk IPI scoreLarge real-world studyAnthracycline-based chemoimmunotherapyHigh-risk IPIComorbidity Index scoreFirst-line therapyProgression-free survivalKaplan-Meier methodCox regression analysisLong-term outcomesLog-rank test