Eye Drop with Fas-Blocking Peptide Attenuates Age-Related Macular Degeneration
Yi Y, Pyun S, Kim C, Yun G, Kang E, Heo S, Ullah I, Lee S. Eye Drop with Fas-Blocking Peptide Attenuates Age-Related Macular Degeneration. Cells 2024, 13: 548. PMID: 38534392, PMCID: PMC10969560, DOI: 10.3390/cells13060548.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsHumansInflammationMacular DegenerationMiceOphthalmic SolutionsPeptidesRabbitsRetinal DegenerationConceptsAge-related macular degenerationDry age-related macular degenerationEye dropsMacular degenerationRetinal degenerationProgression of age-related macular degenerationRetinal degeneration mouse modelEye drop administrationRetinal degeneration modelRetinal cell deathExpression of inflammatory cytokinesLack of effective treatmentsRetinal thicknessAMD progressionIntravitreal administrationDrop administrationInflammatory cytokinesMouse modelEffective treatmentTranslational prospectsRabbit modelTherapeutic potentialFas-mediated apoptosisRetinal regionsSignificant health concern