Featured Publications
Machine learning combining CT findings and clinical parameters improves prediction of length of stay and ICU admission in torso trauma.
Staziaki PV, Wu D, Rayan JC, Santo IDO, Nan F, Maybury A, Gangasani N, Benador I, Saligrama V, Scalera J, Anderson SW. Machine learning combining CT findings and clinical parameters improves prediction of length of stay and ICU admission in torso trauma. European Radiology 2021, 31: 5434-5441. PMID: 33475772, DOI: 10.1007/s00330-020-07534-w.Peer-Reviewed Original ResearchHow to Use YouTube for Radiology Education.
Staziaki PV, Santo IDO, Skobodzinski A, Park LK, Bedi HS. How to Use YouTube for Radiology Education. Current Problems In Diagnostic Radiology 2020 PMID: 33261926, DOI: 10.1067/j.cpradiol.2020.11.007.Peer-Reviewed Original ResearchSequelae of Eating Disorders at Imaging
Solomon N, Sailer A, Dixe de Oliveira Santo I, Pillai A, Heng LXX, Jha P, Katz DS, Zulfiqar M, Sugi M, Revzin MV. Sequelae of Eating Disorders at Imaging. RadioGraphics 2022, 42: 1377-1397. PMID: 35930473, DOI: 10.1148/rg.220018.Peer-Reviewed Educational MaterialsConceptsMedical historyPatient's medical historyHigh mortality rateOverview of managementClinical presentationMedical complicationsRelated complicationsImaging findingsPhysical examinationUncommon sequelaMedical attentionOnline supplemental materialPsychiatric disordersMedical treatmentMortality rateOrgan systemsSequelaeDisordersDiagnosisComplicationsPatientsPathophysiologySocial stigmaLaboratory resultsRadiologistsClinical Implementation of a Combined Artificial Intelligence and Natural Language Processing Quality Assurance Program for Pulmonary Nodule Detection in the Emergency Department Setting
Cavallo J, de Oliveira Santo I, Mezrich J, Forman H. Clinical Implementation of a Combined Artificial Intelligence and Natural Language Processing Quality Assurance Program for Pulmonary Nodule Detection in the Emergency Department Setting. Journal Of The American College Of Radiology 2023, 20: 438-445. PMID: 36736547, DOI: 10.1016/j.jacr.2022.12.016.Peer-Reviewed Original ResearchConceptsEmergency department settingPulmonary nodulesCT examinationsDepartment settingSecondary reviewNumber of patientsQuality assurance studyMedian timeEmergent settingPatient followImaging recommendationsAppropriate followMajority of reviewsRadiological reportsAssurance studyClinical implementationLung anatomyQuality assurance programPatientsSignificant delayNodulesFollowExaminationPulmonary nodule detectionNodule detectionPACS-Integrated Tools for Peritumoral Edema Volumetrics Provide Additional Information to RANO-BM-Based Assessment of Lung Cancer Brain Metastases after Stereotactic Radiotherapy: A Pilot Study
Kaur M, Petersen G, Jekel L, von Reppert M, Varghese S, de Oliveira Santo I, Avesta A, Aneja S, Omuro A, Chiang V, Aboian M. PACS-Integrated Tools for Peritumoral Edema Volumetrics Provide Additional Information to RANO-BM-Based Assessment of Lung Cancer Brain Metastases after Stereotactic Radiotherapy: A Pilot Study. Cancers 2023, 15: 4822. PMID: 37835516, PMCID: PMC10571649, DOI: 10.3390/cancers15194822.Peer-Reviewed Original ResearchPost-SRTStereotactic radiotherapyLung cancer brain metastasesCancer brain metastasesPost-contrast T1-weighted imagesSignificant clinical symptomsContrast-enhancing tumorT1-weighted imagesCritical additional informationEdema changesBrain metastasesClinical symptomsCare treatmentHyperintense volumeEdema assessmentLesion changesLesion sizeEdemaDifferent timepointsPilot studyRadiotherapyLesionsVolumetric changesAdditional informationMETSApplication of novel PACS-based informatics platform to identify imaging based predictors of CDKN2A allelic status in glioblastomas
Tillmanns N, Lost J, Tabor J, Vasandani S, Vetsa S, Marianayagam N, Yalcin K, Erson-Omay E, von Reppert M, Jekel L, Merkaj S, Ramakrishnan D, Avesta A, de Oliveira Santo I, Jin L, Huttner A, Bousabarah K, Ikuta I, Lin M, Aneja S, Turowski B, Aboian M, Moliterno J. Application of novel PACS-based informatics platform to identify imaging based predictors of CDKN2A allelic status in glioblastomas. Scientific Reports 2023, 13: 22942. PMID: 38135704, PMCID: PMC10746716, DOI: 10.1038/s41598-023-48918-4.Peer-Reviewed Original ResearchConceptsInformatics platformDeep learning algorithmsImaging featuresCDKN2A alterationsLearning algorithmHeterozygous lossHomozygous deletionLarge datasetsDeep white matter invasionGBM molecular subtypesNew informaticsQualitative imaging biomarkersWhole-exome sequencingQualitative imaging featuresGBM resectionRadiographic evidenceWorse prognosisPACSMolecular subtypesPial invasionImaging biomarkersCDKN2A mutationsAllele statusNoninvasive identificationMagnetic resonance imagesP13.02.A APPLICATION OF NOVEL PACS-BASED INFORMATICS PLATFORM TO IDENTIFY IMAGING BASED PREDICTORS OF CDKN2A ALLELIC STATUS IN GLIOBLASTOMAS
Tillmanns N, Lost J, Tabor J, Vasandani S, Vetsa S, Marianayagam N, Yalcin K, Erson-Omay Z, von Reppert M, Jekel L, Merkaj S, Ramakrishnan D, Avesta A, de Oliveira Santo I, Jin L, Huttner A, Bousabarah K, Ikuta I, Lin M, Aneja S, Turowski B, Aboian M, Moliterno J. P13.02.A APPLICATION OF NOVEL PACS-BASED INFORMATICS PLATFORM TO IDENTIFY IMAGING BASED PREDICTORS OF CDKN2A ALLELIC STATUS IN GLIOBLASTOMAS. Neuro-Oncology 2023, 25: ii100-ii101. PMCID: PMC10489329, DOI: 10.1093/neuonc/noad137.336.Peer-Reviewed Original ResearchImaging featuresPial invasionQualitative imaging biomarkersQualitative imaging featuresWorse prognosisImaging biomarkersCDKN2A mutationsMethods Sixty-nine patientsCDKN2A alterationsHomozygous deletionHeterozygous lossSixty-nine patientsDeep white matterDeep white matter invasionGBM molecular subtypesWhole-exome sequencingNine patientsGBM resectionRadiographic evidenceMolecular subtypesBACKGROUND GliomasWhite matterAllele statusNoninvasive identificationGliomasGrading Abdominal Trauma: Changes in and Implications of the Revised 2018 AAST-OIS for the Spleen, Liver, and Kidney.
Dixe de Oliveira Santo I, Sailer A, Solomon N, Borse R, Cavallo J, Teitelbaum J, Chong S, Roberge E, Revzin M. Grading Abdominal Trauma: Changes in and Implications of the Revised 2018 AAST-OIS for the Spleen, Liver, and Kidney. RadioGraphics 2023, 43: e230040. PMID: 37590162, DOI: 10.1148/rg.230040.Peer-Reviewed Original ResearchConceptsBlunt abdominal traumaOrgan Injury ScaleAAST-OISOrgan injuryVascular injuryTrauma Organ Injury ScaleLow-grade injuriesMultidetector CT findingsSolid organ injuryHospital mortalityAbdominal traumaCT findingsOrgan damageTrauma centerArteriovenous fistulaTreatment successPatient managementInjury ScaleEarly diagnosisMultidetector CTInjury severityInjuryDisease controlClinical researchInjury detectionKnowledge and Myths about Palliative Care among the General Public and Health Care Professionals in Portugal
dos Anjos Dixe M, de Oliveira Santo I, Lopes S, Catarino H, Duarte S, Querido A, Laranjeira C. Knowledge and Myths about Palliative Care among the General Public and Health Care Professionals in Portugal. International Journal Of Environmental Research And Public Health 2020, 17: 4630. PMID: 32605086, PMCID: PMC7369792, DOI: 10.3390/ijerph17134630.Peer-Reviewed Original ResearchConceptsNonhealthcare professionalsPalliative careHealthcare professionalsPalliative care goalsHealth care professionalsCross-sectional online surveyProgressive diseaseMean ageCare goalsCare professionalsLevel of knowledgePortuguese adultsCareAnonymous questionnaireSignificant differencesDichotomous questionsLife promotionHigh percentageAgeProfessionalsProfessional dataHigh levelsOnline surveyDiseaseDifferent settingsPortuguese knowledge about Palliative Care
European Journal of Public Health, Volume 29, Issue Supplement_2Peer-Reviewed Original ResearchAtitudes dos jovens face à violência nas relações de intimidade (Attitudes of young people to violence in relationships of intimacy).
Dixe MACR, & Santo IDO. Atitudes dos jovens face à violência nas relações de intimidade (Attitudes of young people to violence in relationships of intimacy). Referencia. 2013.Peer-Reviewed Original ResearchSolitary intramuscular myofibroma in an adult: Case report and MR imaging findings.
Santo IDO, Staziaki PV, Prilutskiy A, Sachs TE, Murakami AM. Solitary intramuscular myofibroma in an adult: Case report and MR imaging findings. Clinical Imaging 2020, 67: 95-100. PMID: 32531695, DOI: 10.1016/j.clinimag.2020.05.027.Peer-Reviewed Original ResearchPathology-proven high-grade Parotid gland Mucoepidermoid Carcinoma with distant metastatic disease to bone and lung
Santo IDO, Setty BN. Pathology-proven high-grade Parotid gland Mucoepidermoid Carcinoma with distant metastatic disease to bone and lung. ACR Case in Point. June 14, 2022.Peer-Reviewed Educational MaterialsIntraperitoneal Hematoma After Femoral Catheterization: A Case Report and Literature Review
Shah Z, Khan I, de Oliveira Santo I. Intraperitoneal Hematoma After Femoral Catheterization: A Case Report and Literature Review. Cureus 2022, 14: e25140. PMID: 35733506, PMCID: PMC9205448, DOI: 10.7759/cureus.25140.Peer-Reviewed Original ResearchCentral venous cathetersIntraperitoneal hematomaVena cavaUse of CVCChronic obstructive pulmonary diseaseType 2 diabetes mellitusTwo-day historyObstructive pulmonary diseasePast medical historyIntensive care unitInferior vena cavaSuperior vena cavaCoronavirus disease 2019Skilled nursing facilitiesCVC placementFemoral catheterizationVenous cathetersDiabetes mellitusIll patientsPulmonary diseaseUncommon complicationCare unitEmergency departmentFemoral veinInternal jugularCardiac Amyloidosis: A Rare Cause of Recurrent Chylothorax
Patel R, Shah Z, Santo I, Anwer F, de Oliveira Santo I. Cardiac Amyloidosis: A Rare Cause of Recurrent Chylothorax. Cureus 2022, 14: e24861. PMID: 35702470, PMCID: PMC9177215, DOI: 10.7759/cureus.24861.Peer-Reviewed Original ResearchLeft ventricular hypertrophyCardiac amyloidosisVentricular hypertrophyPleural fluidComputed tomographyPatient underwent video-assisted thoracoscopic surgeryUnderwent video-assisted thoracoscopic surgeryApparent left ventricular hypertrophyVideo-assisted thoracoscopic surgeryPleural catheter placementRight pleural effusionLower lung fieldShortness of breathEvaluation of coughPleural fluid analysisLight chain amyloidosisRecurrent chylothoraxThoracoscopic surgeryElectrocardiographic findingsMechanical ventilationPleural effusionRare causeCatheter placementClinical manifestationsRespiratory statusThe RSNA Cervical Spine Fracture CT Dataset.
Lin H, Colak E, Richards T, Kitamura F, Prevedello L, Talbott J, Ball R, Gumeler E, Yeom K, Hamghalam M, Simpson A, Strika J, Bulja D, Angkurawaranon S, Pérez-Lara A, Gómez-Alonso M, Ortiz Jiménez J, Peoples J, Law M, Dogan H, Altinmakas E, Youssef A, Mahfouz Y, Kalpathy-Cramer J, Flanders A, Abdala N, Brassil M, Crivellaro P, Duh A, Ekladious F, de Mattos Farina E, Gemae M, Huang A, Islam O, Kruscica N, Kushdilian M, Lee R, Merali Z, Moreland R, Natalwalla S, Samorodova O, Shpanskaya Y, Sundaram B, Suthiphosuwan S, Tafur M, Tampieri D, Wilson J, Witiw C, Zia A, D’Anna G, Grayev A, Hierro F, Hollander M, Ikuta I, Lincoln C, Shah L, Singh A, Doyle N, Colon Flores L, Agarwal V, Andersen S, Bailey K, Choudhary G, Chu S, Chung C, Costacurta A, Danial M, de Oliveira Santo I, Dola V, Hsieh K, Khalil A, Lall N, Letourneau-Guillon L, Malin D, Mason J, Montaño M, Moron F, Nath J, Nguyen X, Ormsby J, Oswood M, Ozsarlak O, Rogers S, Rudie J, Sayah A, Schwartz E, Siakallis L, Horner N, de Leão R. The RSNA Cervical Spine Fracture CT Dataset. Radiology Artificial Intelligence 2023, 5: e230034. PMID: 37795143, PMCID: PMC10546361, DOI: 10.1148/ryai.230034.Peer-Reviewed Original ResearchLi-Fraumeni Syndrome: Imaging Features and Guidelines.
Gosangi B, Dixe de Oliveira Santo I, Keraliya A, Wang Y, Irugu D, Thomas R, Khandelwal A, Rubinowitz A, Bader A. Li-Fraumeni Syndrome: Imaging Features and Guidelines. RadioGraphics 2024, 44: e230202. PMID: 39024172, DOI: 10.1148/rg.230202.Peer-Reviewed Original ResearchConceptsLi-Fraumeni syndromeLifetime risk of cancerRare autosomal dominant familial cancer syndromeIncreased riskRisk of cancerTreated with total mastectomyAutosomal dominant familial cancer syndromeImaging features of tumorsFamilial cancer syndromeWhole-body MRIAnnual screeningFeatures of tumorsCancer syndromesLifetime riskP53 transcription factorLi-FraumeniAdrenocortical cancerTotal mastectomyPrimary cancerBreast malignancyImaging guidelinesBreast cancerGermline mutationsColon cancerManagement guidelinesRenovascular hypertension – a primer for the radiologist
Dixe de Oliveira Santo, I., Sindoni, J., Czeyda-Pommersheim, F. et al. Renovascular hypertension – a primer for the radiologist. Abdom Radiol (2024). https://doi.org/10.1007/s00261-024-04677-yPeer-Reviewed Educational MaterialsIncidental Detection of Previously Unknown Strokes on Head CT Examinations: An Untapped Opportunity for Secondary Prevention
Carys L. Kenny-Howell, Irene Dixe de Oliveira Santo, Charles Wira, Adam de Havenon, Long H. Tu, Incidental Detection of Previously Unknown Strokes on Head CT Examinations: An Untapped Opportunity for Secondary Prevention, Journal of the American College of Radiology, 2024, ISSN 1546-1440, https://doi.org/10.1016/j.jacr.2024.11.010.Peer-Reviewed Original Research
2024
IDENTIFICATION OF WHOLE LUNG TORSION ON CT SCAN IMAGING FOLLOWING LINGULA-SPARING LEFT UPPER LOBECTOMY
ZAMAN S, MONTANO M, DE OLIVEIRA SANTO I, TRAUBE L. IDENTIFICATION OF WHOLE LUNG TORSION ON CT SCAN IMAGING FOLLOWING LINGULA-SPARING LEFT UPPER LOBECTOMY. CHEST Journal 2024, 166: a3993-a3994. DOI: 10.1016/j.chest.2024.06.2418.Peer-Reviewed Original Research