2021
Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis
Gaudino M, Hameed I, Di Franco A, Naik A, Demetres M, Biondi-Zoccai G, Bangalore S. Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2021, 165: 1405-1413.e13. PMID: 34176619, PMCID: PMC8805094, DOI: 10.1016/j.jtcvs.2021.05.036.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary artery bypassIncidence rate ratiosCoronary interventionArtery bypassCerebrovascular eventsSYNTAX scoreMultivessel diseaseCause mortalityStatistical heterogeneityRate ratioSystematic reviewCardiac Surgery (SYNTAX) scoreSYNTAX score tertilesCochrane Library databasesMain analysisSignificant statistical heterogeneityRandom-effects modelRevascularization TrialScore tertilesSecondary outcomesSurgery scoreRisk stratificationLibrary databasesNonsignificant increase
2020
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery
Gaudino M, Hameed I, Farkouh ME, Rahouma M, Naik A, Robinson NB, Ruan Y, Demetres M, Biondi-Zoccai G, Angiolillo DJ, Bagiella E, Charlson ME, Benedetto U, Ruel M, Taggart DP, Girardi LN, Bhatt DL, Fremes SE. Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery. JAMA Internal Medicine 2020, 180: 1638-1646. PMID: 33044497, PMCID: PMC7551235, DOI: 10.1001/jamainternmed.2020.4748.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionRandomized clinical trialsCause-specific mortalityCoronary artery diseaseBare metal stentsNoncardiac mortalityCause mortalityCoronary interventionArtery diseaseClinical trialsTrials of PCIEnd pointLeft main diseaseCoronary artery bypassStudy end pointCoronary bypass surgeryData extractionTreatment of patientsCochrane Library databasesPreferred Reporting ItemsRandom-effects modelArtery bypassCardiac mortalityRevascularization TrialBypass surgeryAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational studyRisk of Metachronous Colorectal Neoplasm after a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status
Quezada-Diaz FF, Hameed I, von Mueffling A, Salo-Mullen EE, Catalano A, Smith JJ, Weiser MR, Garcia-Aguilar J, Stadler ZK, Guillem JG. Risk of Metachronous Colorectal Neoplasm after a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status. Journal Of The American College Of Surgeons 2020, 230: 669-675. PMID: 32007537, PMCID: PMC7104918, DOI: 10.1016/j.jamcollsurg.2020.01.005.Peer-Reviewed Original ResearchConceptsLP/P variantsMetachronous colorectal cancerColorectal cancerTotal colectomySegmental resectionSegmental colectomyMMR genesLS patientsLynch syndromeMetachronous colorectal neoplasmsMismatch repair gene statusPrimary end pointRetrospective cohort studyMMR germline mutationsLynch syndrome patientsQuality of lifeMismatch repair genesCRC overallCRC ratesEarly colectomyIndex resectionMedian followMSH2 carriersCRC incidenceCohort study
2019
Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses
Ruan Y, Robinson NB, Naik A, Silva M, Hameed I, Rahouma M, Oakley C, Di Franco A, Zamvar V, Girardi LN, Gaudino M. Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses. International Journal Of Cardiology 2019, 302: 103-107. PMID: 31837901, DOI: 10.1016/j.ijcard.2019.12.009.Peer-Reviewed Original ResearchConceptsPost-operative atrial fibrillationCoronary artery bypassBiA pacingAtrial pacingArtery bypassSecondary outcomesAtrial fibrillationIncidence of POAFGeneric inverse variance methodRight atrial pacingInverse variance methodLargest risk reductionSystematic literature searchPOAF incidenceOperative mortalityPostoperative bleedingPrimary outcomePacing modalitiesClinical trialsLower incidencePacingLiterature searchIncidenceFibrillationRisk reductionCharacteristics and anatomic distribution of early vs late stroke after cardiac surgery
Ivascu NS, Khan FM, Rahouma M, Hameed I, Abouarab A, Segal AZ, Gaudino MFL, Girardi LN. Characteristics and anatomic distribution of early vs late stroke after cardiac surgery. Journal Of Cardiac Surgery 2019, 34: 684-689. PMID: 31212394, DOI: 10.1111/jocs.14121.Peer-Reviewed Original ResearchConceptsLate strokeOperative mortalityCardiac surgeryEarly strokePerioperative strokeOpen cardiac surgeryTime of presentationOpen heart surgeryImpact of strokeWeill Cornell MedicinePerioperative variablesAdult patientsAnterior circulationEmbolic eventsSecondary outcomesCardiopulmonary bypassLikely etiologyAnatomic distributionHeart surgeryRisk factorsAnatomic locationHigh incidencePatientsSurgeryStroke