Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial
Gaudino M, Sanna T, Ballman KV, Robinson NB, Hameed I, Audisio K, Rahouma M, Di Franco A, Soletti GJ, Lau C, Rong LQ, Massetti M, Gillinov M, Ad N, Voisine P, DiMaio JM, Chikwe J, Fremes SE, Crea F, Puskas JD, Girardi L, Investigators P. Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial. The Lancet 2021, 398: 2075-2083. PMID: 34788640, DOI: 10.1016/s0140-6736(21)02490-9.Peer-Reviewed Original ResearchConceptsPericardiotomy groupAtrial fibrillationCardiac surgeryIntervention groupVASc scoreHospital stayHospital dischargePericardial effusionCoronary arteryAortic valvePostoperative major adverse eventsPostoperative atrial fibrillationMajor adverse eventsLeft pleural cavityPostoperative pericardial effusionNew York Presbyterian HospitalEligible patientsITT populationMedian CHATreat populationWeill Cornell MedicinePostoperative complicationsAdult patientsAdverse eventsCommon complication