Featured Publications
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data
Gaudino M, Di Franco A, Alexander JH, Bakaeen F, Egorova N, Kurlansky P, Boening A, Chikwe J, Demetres M, Devereaux PJ, Diegeler A, Dimagli A, Flather M, Hameed I, Lamy A, Lawton JS, Reents W, Robinson NB, Audisio K, Rahouma M, Serruys PW, Hara H, Taggart DP, Girardi LN, Fremes SE, Benedetto U. Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal 2021, 43: 18-28. PMID: 34338767, PMCID: PMC8851663, DOI: 10.1093/eurheartj/ehab504.Peer-Reviewed Original ResearchConceptsCoronary artery bypassIndividual patient dataMyocardial infarctionArtery bypassCause mortalityWorse outcomesMultiple arterial graftingPatient dataOff-pump surgeryOutcomes of womenCABG trialBaseline characteristicsPatients 75Secondary outcomesPrimary outcomeArterial graftingCox regressionPooled analysisSurgical techniqueHigh riskHigh incidenceSimilar mortalitySystematic reviewRisk adjustmentMortality
2020
Treatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis
Gaudino M, Hameed I, Khan FM, Tam DY, Rahouma M, Yongle R, Naik A, Di Franco A, Demetres M, Petrie MC, Jolicoeur EM, Girardi LN, Fremes SE. Treatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis. European Journal Of Cardio-Thoracic Surgery 2020, 59: 293-301. PMID: 33085752, DOI: 10.1093/ejcts/ezaa319.Peer-Reviewed Original ResearchPercutaneous coronary interventionIschemic left ventricular systolic dysfunctionMedical therapyCardiac deathMyocardial infarctionRevascularization strategyHigh mortalityLeft ventricular systolic dysfunctionIschemic left ventricular dysfunctionLeft ventricular ejection fractionBest revascularization strategyLower cardiac deathOptimal revascularization strategyCoronary artery bypassVentricular systolic dysfunctionLeft ventricular dysfunctionVentricular ejection fractionDrug-eluting stentsRelative treatment effectsArtery bypassSystolic dysfunctionVentricular dysfunctionCoronary interventionSecondary outcomesEjection fractionImpact of Operator Characteristics on Outcomes in Transcatheter Aortic Valve Replacement
Rong LQ, Gaudino M, Tam D, Mao J, Zheng X, Hameed I, Khan F, Salemi A, Sedrakyan A, Neuburger PJ, Fremes S. Impact of Operator Characteristics on Outcomes in Transcatheter Aortic Valve Replacement. The Annals Of Thoracic Surgery 2020, 111: 853-860. PMID: 32795521, DOI: 10.1016/j.athoracsur.2020.06.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement (TAVR) proceduresAortic valve replacement proceduresAortic valve replacementAcute myocardial infarctionHealth Statewide PlanningValve replacement proceduresOperator characteristicsInhospital outcomesTAVR volumeInhospital mortalityValve replacementPrimary outcomeMyocardial infarctionSubgroup analysisStatewide PlanningProvider characteristicsCardiology practiceNew York State DepartmentInterventional cardiologyTAVROperator specialtyReplacement proceduresMedical school locationSignificant differencesSex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol
Gaudino M, Alexander JH, Egorova N, Kurlansky P, Lamy A, Bakaeen F, Hameed I, Di Franco A, Demetres M, Robinson NB, Chikwe J, Lawton JS, Devereaux PJ, Taggart DP, Flather M, Reents W, Boening A, Diegeler A, Girardi LN, Fremes SE, Benedetto U. Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal Of Cardiac Surgery 2020, 35: 2754-2758. PMID: 32720394, DOI: 10.1111/jocs.14903.Peer-Reviewed Original ResearchConceptsSex-related differencesPooled analysisSystematic reviewPatient-level pooled analysisCoronary artery bypass surgeryMultiple arterial graftsArtery bypass surgeryCoronary artery bypassLong-term followSex-related outcomesTreatment effectsPreferred Reporting ItemsSystematic literature searchPeer-reviewed scientific journalsImpact of sexDifferential treatment effectsCABG studiesArtery bypassCause mortalityPrimary endpointBypass surgeryArterial graftsMyocardial infarctionStudy protocolProspective RegisterAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational studyOpen Repair of Descending Thoracic and Thoracoabdominal Aortic Aneurysms: A Meta-Analysis
Khan FM, Naik A, Hameed I, Robinson NB, Spadaccio C, Rahouma M, Yongle R, Demetres M, Chen H, Chang M, Girardi LN, Gaudino M. Open Repair of Descending Thoracic and Thoracoabdominal Aortic Aneurysms: A Meta-Analysis. The Annals Of Thoracic Surgery 2020, 110: 1941-1949. PMID: 32504596, DOI: 10.1016/j.athoracsur.2020.04.069.Peer-Reviewed Original ResearchConceptsThoracoabdominal aortic aneurysmsCerebrospinal fluid drainsOpen repairOperative mortalitySpinal cord injuryAortic aneurysmLate mortalityRespiratory failureRenal failureCord injuryMyocardial infarctionGeneric inverse variance methodFluid drainsHigh operative mortalityLow operative mortalityInverse variance methodThoracic aortic aneurysmSystematic literature searchPostoperative strokeOperative deathsPerioperative complicationsPostoperative outcomesSecondary outcomesPrimary outcomePooled rateDiagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review
Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M. Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review. International Journal Of Surgery 2020, 79: 76-83. PMID: 32442689, PMCID: PMC7853700, DOI: 10.1016/j.ijsu.2020.05.036.Peer-Reviewed Original ResearchConceptsPerioperative myocardial infarctionCoronary artery bypassArtery bypassMyocardial infarctionPost-operative echocardiographyProcedure-related changesPerioperative morbidityPost-procedure changesCardiac proceduresSignificant complicationsDiagnostic dilemmaPatient outcomesCardiac biomarkersCABGClinical settingDiagnostic testsPerfect diagnostic testInfarctionBypassUnited StatesModalitiesSpecific modalitiesOutcomesMorbidityEchocardiography
2019
Sinus of Valsalva aneurysm repairs: Operative technique and lessons learned
Wingo M, de Angelis P, Worku BM, Leonard JR, Khan FM, Hameed I, Lau C, Gaudino M, Girardi LN. Sinus of Valsalva aneurysm repairs: Operative technique and lessons learned. Journal Of Cardiac Surgery 2019, 34: 400-403. PMID: 30953447, DOI: 10.1111/jocs.14041.Peer-Reviewed Original ResearchConceptsSOV aneurysmAneurysm repairSingle tertiary referral centerRight ventricular outflow tractPulmonary artery compressionValsalva aneurysm repairYears underwent repairTertiary referral centerVentricular outflow tractBentall procedureArtery compressionOperative interventionPostoperative periodReferral centerValsalva aneurysmUnderwent repairOperative managementPrimary aneurysmMean ageMyocardial infarctionAneurysm diameterOutflow tractOperative techniqueAneurysm recurrenceSafe option
2018
Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis
Leonard JR, Henry M, Rahouma M, Khan FM, Wingo M, Hameed I, Di Franco A, Guy TS, Girardi LN, Gaudino M. Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis. International Journal Of Cardiology 2018, 278: 300-306. PMID: 30563771, DOI: 10.1016/j.ijcard.2018.12.025.Peer-Reviewed Original ResearchConceptsPost-operative strokeInvasive mitral valve surgeryPooled event rateMitral valve surgeryCT screeningOperative mortalityValve surgeryMyocardial infarctionCT groupNew-onset renal failureLow operative mortalityPerioperative myocardial infarctionCardio-pulmonary bypassComputed Tomography ScreeningPreoperative CT scanRetrograde arterial perfusionInter-group comparisonAortic embolizationNew dialysisPerioperative strokeRenal failureTomography screeningArterial perfusionDecreased incidenceSurgical approach