2021
Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial
Gaudino M, Sanna T, Ballman KV, Robinson NB, Hameed I, Audisio K, Rahouma M, Di Franco A, Soletti GJ, Lau C, Rong LQ, Massetti M, Gillinov M, Ad N, Voisine P, DiMaio JM, Chikwe J, Fremes SE, Crea F, Puskas JD, Girardi L, Investigators P. Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial. The Lancet 2021, 398: 2075-2083. PMID: 34788640, DOI: 10.1016/s0140-6736(21)02490-9.Peer-Reviewed Original ResearchConceptsPericardiotomy groupAtrial fibrillationCardiac surgeryIntervention groupVASc scoreHospital stayHospital dischargePericardial effusionCoronary arteryAortic valvePostoperative major adverse eventsPostoperative atrial fibrillationMajor adverse eventsLeft pleural cavityPostoperative pericardial effusionNew York Presbyterian HospitalEligible patientsITT populationMedian CHATreat populationWeill Cornell MedicinePostoperative complicationsAdult patientsAdverse eventsCommon complication
2020
Effect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement
Robinson NB, Hameed I, Naik A, Ishtiaq MF, Rahouma M, Girardi LN, Gaudino M. Effect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement. The Annals Of Thoracic Surgery 2020, 110: 2041-2046. PMID: 32343949, PMCID: PMC7799918, DOI: 10.1016/j.athoracsur.2020.03.070.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAorta replacementOperative mortalityConcomitant CABGRisk of MAEsConcomitant coronary artery bypassCoronary artery bypass graftEnd pointConcomitant coronary revascularizationPreoperative pulmonary dysfunctionPrimary end pointSecondary end pointsCoronary artery bypassPerioperative myocardial infarctionArtery bypass graftOnly independent predictorHigh-volume centersAscending Aorta ReplacementCABG groupArtery bypassCoronary revascularizationPulmonary dysfunctionUnadjusted incidenceAdverse eventsPostoperative outcomes
2019
Impact of left ventricular ejection fraction on the outcomes of open repair of descending thoracic and thoracoabdominal aneurysms
Gambardella I, Gaudino MFL, Rahouma M, Farrington WJ, Khan FM, Hameed I, Lau C, Iannacone E, Girardi LN. Impact of left ventricular ejection fraction on the outcomes of open repair of descending thoracic and thoracoabdominal aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2019, 161: 534-541.e5. PMID: 31924362, DOI: 10.1016/j.jtcvs.2019.11.009.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionDepressed left ventricular ejection fractionVentricular ejection fractionCubic spline analysisOperative mortalityIndependent predictorsAdverse eventsEjection fractionWorse long-term survivalRisk of MAEThoracoabdominal aneurysm repairWorse preoperative profilesMajor adverse eventsSpline analysisLong-term survivalTAAA repairThoracoabdominal aneurysmsOpen repairAneurysm repairThoracic aneurysmCox regressionPreoperative profilesMortalityMultivariate regressionPatients