2023
The Predictors of Complete Pathologic Response in Rectal Cancer during the Total Neoadjuvant Therapy Era: A Systematic Review
Flom E, Schultz K, Pantel H, Leeds I. The Predictors of Complete Pathologic Response in Rectal Cancer during the Total Neoadjuvant Therapy Era: A Systematic Review. Cancers 2023, 15: 5853. PMID: 38136397, PMCID: PMC10742121, DOI: 10.3390/cancers15245853.Peer-Reviewed Original ResearchTotal neoadjuvant therapyPathologic complete responseClinical complete responseNeoadjuvant therapyComplete responseSystematic reviewRectal cancerTumor responseClinical stage 2Complete pathologic responseRetrospective cohort studyRandomized clinical trialsHeterogeneity of studiesLevel of evidenceElectronic databases EmbaseIdentification of predictorsCancer treatment paradigmLong-term trialsNeoadjuvant chemotherapyTherapy eraPatient demographicsPreoperative predictorsClinical factorsClinicopathologic factorsCohort study
2022
Short- and Long-term Outcomes of Ileal Pouch Anal Anastomosis Construction in Obese Patients With Ulcerative Colitis
Leeds IL, Holubar SD, Hull TL, Lipman JM, Lightner AL, Sklow B, Steele SR. Short- and Long-term Outcomes of Ileal Pouch Anal Anastomosis Construction in Obese Patients With Ulcerative Colitis. Diseases Of The Colon & Rectum 2022, 65: e782-e789. PMID: 34958050, DOI: 10.1097/dcr.0000000000002169.Peer-Reviewed Original ResearchConceptsLong-term pouch failureObese patientsUlcerative colitisNonobese patientsPostoperative complicationsPouch failurePouch surgeryColitis ulcerosaASA class 3Intraoperative technical difficultiesOutcomes of obeseAssociation of obesityPouch failure rateWorse clinical outcomesQuaternary referral centerLong-term outcomesLength of stayIleoanal pouch surgeryQuality of lifePouch leakPouch survivalPreoperative steroidsASA 3Anastomotic leakCohort study
2017
Racial and Socioeconomic Differences Manifest in Process Measure Adherence for Enhanced Recovery After Surgery Pathway
Leeds IL, Alimi Y, Hobson DR, Efron JE, Wick EC, Haut ER, Johnston FM. Racial and Socioeconomic Differences Manifest in Process Measure Adherence for Enhanced Recovery After Surgery Pathway. Diseases Of The Colon & Rectum 2017, 60: 1092-1101. PMID: 28891854, PMCID: PMC5647878, DOI: 10.1097/dcr.0000000000000879.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCohort StudiesColectomyColonic DiseasesColorectal SurgeryElective Surgical ProceduresFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePatient CompliancePostoperative ComplicationsQuality ImprovementRacial GroupsSocioeconomic FactorsUnited StatesConceptsSurgery pathwayPathway implementationSocioeconomic statusWhite patientsPopulation subgroupsOverall adherenceShort-term surgical outcomesTertiary academic medical centerProcess measure adherenceThirty-day outcomesEnhanced recovery pathwayProcess measuresAcademic medical centerHigher socioeconomic statusElective colonPreoperative characteristicsQuality improvement purposesCohort studyComplication rateNonwhite patientsRectal resectionPain therapyMedian lengthSurgical outcomesMedical Center