Featured Publications
Recurrent DNA copy number variation in the laboratory mouse
Egan CM, Sridhar S, Wigler M, Hall IM. Recurrent DNA copy number variation in the laboratory mouse. Nature Genetics 2007, 39: 1384-1389. PMID: 17965714, DOI: 10.1038/ng.2007.19.Peer-Reviewed Original ResearchConceptsCopy number variationsCopy numberNumber variationsGenome-wide analysisDNA copy number variationsRecent common ancestryGenerations of inbreedingRecurrent copy number variationsHigh-resolution microarraysCommon ancestryNatural variationGenetic differencesDifferent speciesDifferent lociGenerational timeLaboratory miceNonrandom processGenomeRecurrent mutationsLociAdditional strainsInbreedingLineagesGenesDiscrete segments
2019
Exome sequencing of Finnish isolates enhances rare-variant association power
Locke AE, Steinberg KM, Chiang CWK, Service SK, Havulinna AS, Stell L, Pirinen M, Abel HJ, Chiang CC, Fulton RS, Jackson AU, Kang CJ, Kanchi KL, Koboldt DC, Larson DE, Nelson J, Nicholas TJ, Pietilä A, Ramensky V, Ray D, Scott LJ, Stringham HM, Vangipurapu J, Welch R, Yajnik P, Yin X, Eriksson JG, Ala-Korpela M, Järvelin MR, Männikkö M, Laivuori H, Dutcher S, Stitziel N, Wilson R, Hall I, Sabatti C, Palotie A, Salomaa V, Laakso M, Ripatti S, Boehnke M, Freimer N. Exome sequencing of Finnish isolates enhances rare-variant association power. Nature 2019, 572: 323-328. PMID: 31367044, PMCID: PMC6697530, DOI: 10.1038/s41586-019-1457-z.Peer-Reviewed Original Research