Dynamic right ventricular–pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension
Singh I, Rahaghi F, Naeije R, Oliveira R, Vanderpool RR, Waxman A, Systrom D. Dynamic right ventricular–pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension. Pulmonary Circulation 2019, 9: 1-10. PMID: 31218910, PMCID: PMC6643191, DOI: 10.1177/2045894019862435.Peer-Reviewed Original ResearchPulmonary arterial hypertensionExercise pulmonary hypertensionRV-PA couplingMaximum incremental exerciseRV-PA uncouplingPulmonary hypertensionExercise pHRV contractilityArterial hypertensionExercise capacityIncremental exerciseInvasive cardiopulmonary exercise testingReduced peak oxygen consumptionPressure-volume loop analysisPulmonary arterial elastanceCardiopulmonary exercise testingRight ventricular functionPeak oxygen consumptionAge-matched controlsEnd-systolic elastanceContractile reserveExercise testingRV functionSuch patientsVentricular function