2020
Initial posaconazole dosing to achieve therapeutic serum posaconazole concentrations among children, adolescents, and young adults receiving delayed‐release tablet and intravenous posaconazole
Bernardo V, Miles A, Fernandez AJ, Liverman R, Tippett A, Yildirim I. Initial posaconazole dosing to achieve therapeutic serum posaconazole concentrations among children, adolescents, and young adults receiving delayed‐release tablet and intravenous posaconazole. Pediatric Transplantation 2020, 24: e13777. PMID: 32639095, DOI: 10.1111/petr.13777.Peer-Reviewed Original ResearchConceptsYears of ageMedian daily doseTrough concentrationsDaily dosePlasma concentrationsYoung adultsPlasma trough concentrationsSerum posaconazole concentrationsInvasive fungal diseaseTherapeutic plasma concentrationsDelayed-release tabletsIntravenous posaconazolePosaconazole dosingImmunocompromised childrenPatients 13Optimal dosingBroad-spectrum antifungalsAdolescent patientsPosaconazole concentrationsHigher dosingPatientsBody weightGrade 1ProphylaxisDosing
2018
Necrotizing fasciitis caused by Mucor indicus in a pediatric bone marrow transplant recipient
Bloch D, Gonzalez MD, Haight A, Abramowsky C, Yildirim I. Necrotizing fasciitis caused by Mucor indicus in a pediatric bone marrow transplant recipient. Pediatric Transplantation 2018, 22: e13294. PMID: 30246483, PMCID: PMC6460914, DOI: 10.1111/petr.13294.Peer-Reviewed Original ResearchConceptsPediatric bone marrow transplant recipientsBone marrow transplant recipientsMarrow transplant recipientsLiposomal amphotericin BSubcutaneous cellular tissueMultiple debridementsTransplant recipientsCase reportRare fungal organismRisk factorsAmphotericin BSusceptibility testingFasciitisFungal organismsAnaerobic bacteria