SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity
Jaycox J, Lucas C, Yildirim I, Dai Y, Wang E, Monteiro V, Lord S, Carlin J, Kita M, Buckner J, Ma S, Campbell M, Ko A, Omer S, Lucas C, Speake C, Iwasaki A, Ring A. SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity. Nature Communications 2023, 14: 1299. PMID: 36894554, PMCID: PMC9996559, DOI: 10.1038/s41467-023-36686-8.Peer-Reviewed Original ResearchConceptsVaccine-associated myocarditisAutoimmune patientsAutoantibody reactivitySARS-CoV-2 mRNA vaccinationVaccine-related adverse effectsSARS-CoV-2 immunitySARS-CoV-2 infectionAcute COVID-19Development of autoantibodiesCOVID-19 patientsAnti-viral immunityVirus-specific antibodiesCOVID-19 vaccineCOVID-19Humoral autoimmunityMRNA vaccinationAutoantibody responsePost vaccinationAutoantibody developmentAutoimmune diseasesHumoral responseHealthy individualsPatientsAntigen profilingAdverse effectsEvidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population
Lind M, Dorion M, Houde A, Lansing M, Lapidus S, Thomas R, Yildirim I, Omer S, Schulz W, Andrews J, Hitchings M, Kennedy B, Richeson R, Cummings D, Ko A. Evidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population. Nature Communications 2023, 14: 5055. PMID: 37598213, PMCID: PMC10439918, DOI: 10.1038/s41467-023-40750-8.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionPrior infectionHybrid immunityInfection riskCOVID-19 vaccinationNon-pharmaceutical interventionsInfected residentsVaccinationInfectionDocumented exposureDelta periodCell exposureIncarcerated populationsExposureImmunityRiskAssociationPotential benefitsCorrectional facilitiesCrowded settingsResidentsPeriodCOVID-19 Vaccine Acceptance and Hesitancy Among Health Care Workers in Lebanon
Youssef N, Tfaily N, Moumneh M, Boutros C, Elharake J, Malik A, McFadden S, Galal B, Yildirim I, Khoshnood K, Omer S, Memish Z, Dbaibo G. COVID-19 Vaccine Acceptance and Hesitancy Among Health Care Workers in Lebanon. Journal Of Epidemiology And Global Health 2023, 13: 55-66. PMID: 36735184, PMCID: PMC9896451, DOI: 10.1007/s44197-023-00086-4.Peer-Reviewed Original ResearchConceptsHealth care workersCOVID-19 vaccine acceptanceVaccine acceptancePrevious infectionCare workersPrevious SARS-CoV-2 infectionSARS-CoV-2 infectionMethodsA cross-sectional studyCOVID-19 vaccination ratesCOVID-19 vaccinationCross-sectional studyCOVID-19 vaccineHealth care authoritiesVaccine uptakeVaccination ratesOrder of PhysiciansVaccine hesitancyGeneral populationHealthcare providersVaccineCare authoritiesInfectionCOVID-19 informationTrusted sourceCOVID-19 pandemic