2024
Development and comparison of immunologic assays to detect primary RSV infections in infants
Anderson L, Jadhao S, Hussaini L, Ha B, McCracken C, Gibson T, Yildirim I, Yi J, Stephens K, Korski C, Kao C, Sun H, Lee C, Jaunarajs A, Rostad C, Anderson E. Development and comparison of immunologic assays to detect primary RSV infections in infants. Frontiers In Immunology 2024, 14: 1332772. PMID: 38283339, PMCID: PMC10811012, DOI: 10.3389/fimmu.2023.1332772.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusIgG enzyme immunoassayNeutralizing antibody assaysELISPOT assayAntibody assayRSV antibodiesEnzyme immunoassayRSV infectionSubgroup ARespiratory syncytial virus seasonDocumented RSV infectionPrimary RSV infectionEffective respiratory syncytial virusVaccine clinical trialsEvidence of past infectionEpidemiological studiesRed cell lysisYoung childrenMaternal microchimerismPBMC specimensPregnant womenIFN-gSyncytial virusAntibody enzyme immunoassayELISPOT
2020
Differences in maternal group B Streptococcus screening rates in Latin American countries
HogenEsch E, De Mucio B, Haddad LB, Vilajeliu A, Ropero AM, Yildirim I, Omer SB. Differences in maternal group B Streptococcus screening rates in Latin American countries. Vaccine 2020, 39: b3-b11. PMID: 33308886, DOI: 10.1016/j.vaccine.2020.10.082.Peer-Reviewed Original ResearchConceptsMaternal GBS screeningMaternal GBS colonizationGBS screeningGBS colonizationScreening ratesPregnant womenGroup B Streptococcus ScreeningMaternal group B StreptococcusLogistic regressionGBS colonization prevalenceIntrapartum antibiotic treatmentMaternal GBS vaccineNeonatal GBS diseaseAdverse neonatal outcomesRetrospective observational studyMaternal age groupsGroup B streptococciDemographic variablesLower ratesGBS prevalenceFinal regression modelGBS diseaseNeonatal outcomesNeonatal sepsisGBS vaccineChapter 6 Tetanus
Yildirim I, Omer S. Chapter 6 Tetanus. 2020, 115-130. DOI: 10.1016/b978-0-12-814582-1.00007-3.Peer-Reviewed Original ResearchNeonatal tetanusTetanus toxoidPregnant womenCare practicesNeonatal tetanus elimination programHigh routine immunization coverageCord care practicesMaternal tetanus vaccinationNeonatal care practicesRoutine immunization coverageWorld Health AssemblyMaternal tetanusTetanus incidenceTetanus vaccinationMaternal immunizationChildhood vaccinesNeonatal mortalityLeading causeImmunization coverageClean deliveryElimination programTetanusToxoidHealth AssemblySafe strategy
2019
3162 Colonization of Pregnant Women with Group B streptococcus in Latin America and Infant Outcomes
HogenEsch E, Haddad L, Yildirim I, Omer S. 3162 Colonization of Pregnant Women with Group B streptococcus in Latin America and Infant Outcomes. Journal Of Clinical And Translational Science 2019, 3: 37-38. PMCID: PMC6808231, DOI: 10.1017/cts.2019.92.Peer-Reviewed Original ResearchMaternal GBS colonizationGBS colonizationPreterm birthCesarean sectionPregnant womenRisk factorsGBS diseasePerinatal outcomesMaternal colonizationPrevalence ratesExact testSignificant associationMultiple logistic regression modelBurden of stillbirthsGBS colonization statusGBS-negative mothersGBS-positive mothersMaternal GBS carriageNeonatal GBS diseasePerinatal health indicatorsSpecific perinatal outcomesIncidence of sepsisClinical risk factorsWeeks of gestationGroup B streptococci