Comparison of nasopharyngeal culture, polymerase chain reaction (PCR) and serological test for diagnosis of pertussis.
Cengiz AB, Yildirim I, Ceyhan M, Seçmeer G, Gür D, Kara A. Comparison of nasopharyngeal culture, polymerase chain reaction (PCR) and serological test for diagnosis of pertussis. The Turkish Journal Of Pediatrics 2009, 51: 309-16. PMID: 19950836.Peer-Reviewed Original ResearchConceptsDiagnosis of pertussisFirst serum samplePolymerase chain reactionIgG antibodiesSerum samplesNasopharyngeal culturesPertussis toxinInitial examinationHacettepe University Ihsan Doğramaci Children's HospitalB. pertussisAnti-pertussis antibodiesSecond serum samplePCR-positive patientsB. pertussis antigensChain reactionTypes of antibodiesBordetella pertussis cultureAntibody positivityParoxysmal coughPertussis antigensVaccination historyAntibody levelsChildren's HospitalProspective studyInspiratory whoop