2021
Population-Based Surveillance of Pneumococcal Infections in Children with Sickle Cell Disease before and after Prevnar 7® and Prevnar 13® Licensure: Implications for Expanded Vaccination
Adamkiewicz T, Thomas S, Tunali A, Lai K, Yee M, Yildirim I, Lane P, Omole F, Farley M. Population-Based Surveillance of Pneumococcal Infections in Children with Sickle Cell Disease before and after Prevnar 7® and Prevnar 13® Licensure: Implications for Expanded Vaccination. Blood 2021, 138: 763. DOI: 10.1182/blood-2021-154474.Peer-Reviewed Original ResearchInvasive pneumococcal diseaseSickle cell diseaseIPD ratesPCV periodPCV7 licensureMean ageRelative riskCell diseaseGeneral populationNew vaccinesNon-PCV13 serotypesPneumococcal polysaccharide vaccineRegistry of patientsPopulation-based surveillanceProphylactic antibiotic useEmory University Institutional Review BoardAntibiotic susceptibility testingInstitutional review boardUniversity Institutional Review BoardAge of infectionIPD diagnosisPCV eraPCV13 periodPCV13 serotypesPCV7 period
2015
Vaccination, Underlying Comorbidities, and Risk of Invasive Pneumococcal Disease
Yildirim I, Shea KM, Little BA, Silverio AL, Pelton SI. Vaccination, Underlying Comorbidities, and Risk of Invasive Pneumococcal Disease. Pediatrics 2015, 135: 495-503. PMID: 25647674, DOI: 10.1542/peds.2014-2426.Peer-Reviewed Original ResearchMeSH KeywordsBacterial CapsulesChildChild, PreschoolComorbidityFemaleFollow-Up StudiesHumansIncidenceInfantMaleMassachusettsPneumococcal InfectionsPneumococcal VaccinesPopulation SurveillancePrognosisRetrospective StudiesRisk AssessmentRisk FactorsStreptococcus pneumoniaeVaccinationVaccines, ConjugateConceptsInvasive pneumococcal diseasePneumococcal diseaseUnderlying conditionOutcomes of IPDPrevention of IPDChildhood invasive pneumococcal diseasePneumococcal vaccination statusPolysaccharide pneumococcal vaccineYear of diagnosisPrimary care providersCase fatality rateChronic respiratory diseasesImmunocompromising conditionsIPD diagnosisUnderlying comorbiditiesImmunization PracticesIPD casesPneumococcal vaccineVaccination statusConjugate vaccineMassachusetts childrenClinical presentationSerotype distributionHigher hospitalizationClinical data