2021
#18: Brincidofovir for the Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid-organ Transplant Recipients
Londeree J, Garro R, Romero R, George R, Winterberg P, Liverman R, Serluco A, Shin S, Yildirim I. #18: Brincidofovir for the Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid-organ Transplant Recipients. Journal Of The Pediatric Infectious Diseases Society 2021, 10: s3-s3. DOI: 10.1093/jpids/piaa170.008.Peer-Reviewed Original ResearchPediatric SOT patientsAcute kidney injuryHAdV infectionSolid organ transplantationSOT patientsSevere diseaseResolution of AKIPediatric solid organ transplant recipientsSolid organ transplant recipientsAntiviral treatment optionsInvestigational antiviral drugsPediatric transplant centersBaseline clinical characteristicsDays of therapyMainstay of treatmentResolution of symptomsSubset of patientsHuman adenovirus infectionHAdV viral loadsAdenovirus viremiaBaseline creatinineGraft involvementGraft lossHAdV viremiaReduced immunosuppression
2020
Brincidofovir for the treatment of human adenovirus infection in pediatric solid organ transplant recipients: A case series
Londeree J, Winterberg PD, Garro R, George RP, Shin S, Liverman R, Serluco A, Romero R, Yildirim I. Brincidofovir for the treatment of human adenovirus infection in pediatric solid organ transplant recipients: A case series. Pediatric Transplantation 2020, 24: e13769. PMID: 32558134, DOI: 10.1111/petr.13769.Peer-Reviewed Original ResearchConceptsPediatric SOT recipientsSOT recipientsCase seriesSevere diseasePediatric solid organ transplant recipientsSolid organ transplant recipientsType of allograftMainstay of treatmentOrgan transplant recipientsSeverity of diseaseHuman adenovirus infectionHAdV diseaseHAdV viremiaPediatric recipientsTransplant recipientsHAdV infectionDisease courseAntiviral therapySignificant morbidityDisease presentationUS FDAAdenovirus infectionBrincidofovirDiseaseRecipients