Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine
Anderson EJ, Lai L, Wrammert J, Kabbani S, Xu Y, Priyamvada L, Hill H, Goll JB, Jensen TL, Kao C, Yildirim I, Rouphael N, Jackson L, Mulligan MJ. Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine. Vaccines 2020, 8: 69. PMID: 32041104, PMCID: PMC7158692, DOI: 10.3390/vaccines8010069.Peer-Reviewed Original ResearchMemory B cellsPlaque reduction neutralization testVaccinia Ankara vaccineCD4 T cellsT cellsB cellsDay 1Follicular helper T cell responsesIgG-secreting B cellsModified Vaccinia Ankara VaccineFollicular helper T cellsHelper T cell responsesVaccinia-specific antibodiesT cell responsesHelper T cellsReduction neutralization testEnzyme-linked immunosorbentSecond vaccineEvaluable specimensInjection recipientsPRNT titersDay 29Neutralization testPlasmablastsNovel vaccines