All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity[S]
Ding T, Kabir I, Li Y, Lou C, Yazdanyar A, Xu J, Dong J, Zhou H, Park T, Boutjdir M, Li Z, Jiang XC. All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity[S]. Journal Of Lipid Research 2015, 56: 537-545. PMID: 25605874, PMCID: PMC4340302, DOI: 10.1194/jlr.m054627.Peer-Reviewed Original ResearchConceptsCeramide phosphoethanolamineCPE levelsSynthase activityObvious phenotypic alterationsSynthase gene familySf9 insect cellsQuantitative MS analysisGene familyCeramide homeostasisInsect cellsCritical regulatorNBD-ceramideSMS2 activityPhenotypic alterationsSMS1SMS1 deficiencySphingolipid levelsSMS2Ceramide levelsCell functionKO miceCell studiesMS analysisFamily membersCells