The effect of methylprednisolone on warm ischemia-reperfusion injury in the liver
Saidi RF, Chang J, Verb S, Brooks S, Nalbantoglu I, Adsay V, Jacobs MJ. The effect of methylprednisolone on warm ischemia-reperfusion injury in the liver. The American Journal Of Surgery 2007, 193: 345-348. PMID: 17320532, DOI: 10.1016/j.amjsurg.2006.09.017.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injuryR injuryInterleukin-6Continuous clampingIschemic preconditioningSteatotic liversInflammatory responseNormal liverAspartate aminotransferaseLiver ischemia-reperfusion injuryWarm ischemia-reperfusion injuryMale Sprague-Dawley ratsSerum IL-6Serum interleukin-6Hours of reperfusionEffect of methylprednisoloneCause of morbiditySprague-Dawley ratsIntravenous methylprednisoloneHepatic ischemiaIschemia inductionSerum levelsIschemic controlsIschemic periodLiver ischemia