European genetic ancestry is associated with a decreased risk of lupus nephritis
Richman IB, Taylor KE, Chung SA, Trupin L, Petri M, Yelin E, Graham RR, Lee A, Behrens TW, Gregersen PK, Seldin MF, Criswell LA. European genetic ancestry is associated with a decreased risk of lupus nephritis. Arthritis & Rheumatism 2012, 64: 3374-3382. PMID: 23023776, PMCID: PMC3865923, DOI: 10.1002/art.34567.Peer-Reviewed Original ResearchMeSH KeywordsAdultAllelesAsian PeopleBlack PeopleCross-Sectional StudiesFemaleGenetic Predisposition to DiseaseGenotypeHLA AntigensHumansLupus NephritisMaleMiddle AgedPolymorphism, Single NucleotideRiskWhite PeopleConceptsSystemic lupus erythematosusRenal diseaseLupus nephritisSLE patientsSingle nucleotide polymorphismsSocioeconomic statusEuropean genetic ancestryCross-sectional studyEuropean ancestrySocioeconomic factorsCandidate risk allelesSubset of participantsMeasures of SESDisease durationLupus erythematosusDecreased riskLogistic regressionDiseaseRisk allelesGenetic ancestryNephritisEuropean descentPatientsCandidate genesAfrican Americans