Correlation of TILs indices generated by visual review and digital computational algorithm with outcomes from preoperative chemotherapy for TNBC in TBCRC 030.
Nader Marta G, Chu X, Mukhopadhyay S, Abramson V, Brufsky A, Stringer-Reasor E, Dent S, Traina T, Carey L, Rimawi M, Specht J, Miller K, Santa-Maria C, Dasgupta T, Binboğa Kurt B, Tayob N, Krop I, Tung N, Schnitt S, Mayer E. Correlation of TILs indices generated by visual review and digital computational algorithm with outcomes from preoperative chemotherapy for TNBC in TBCRC 030. Journal Of Clinical Oncology 2024, 42: 555-555. DOI: 10.1200/jco.2024.42.16_suppl.555.Peer-Reviewed Original ResearchTriple negative breast cancerTumor-infiltrating lymphocytesArea under the curveEvaluation of tumor-infiltrating lymphocytesCore needle biopsyNeoadjuvant chemotherapyPredictive of responseOdds ratioReceiver operating characteristicImmune microenvironmentEarly-stage triple negative breast cancerPre-treatment core needle biopsyPrediction of response to NACBaseline tumor-infiltrating lymphocytesEvaluate tumor-infiltrating lymphocytesStromal tumor-infiltrating lymphocytesResponse to NACTumor-infiltrating lymphocyte scoresResponse to neoadjuvant chemotherapyImmune responseCombined immune responseNegative breast cancerH&E-stained slidesCell cycle aberrationsCell cycle signature