Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors.
Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K. Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors. Cancer Research 2003, 63: 2024-7. PMID: 12727813.Peer-Reviewed Original ResearchConceptsHIN-1 methylationBreast tumorsHIN-1BRCA1 tumorsSporadic breast tumorsFamilial breast cancer patientsBreast cancer patientsSpecific breast cancer subtypesBreast cancer riskBreast cancer subtypesSporadic breast carcinomasGerm-line mutationsPromoter methylation statusCancer patientsHER2 statusBreast carcinomaHistopathological phenotypeEstrogen receptorCancer riskCandidate tumor suppressor geneCancer subtypesSporadic casesTumorsCancer typesTumor suppressor gene