1976
The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung
Gross I, Ilic I, Wilson C, Rooney S. The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung. Biochimica Et Biophysica Acta 1976, 441: 412-422. PMID: 9987, DOI: 10.1016/0005-2760(76)90238-1.Peer-Reviewed Original ResearchConceptsLung cell numberLung lavage phospholipidPostnatal nutritional deprivationTotal phospholipidsStandard rat chowLung protein contentPhosphatidylcholine contentRole of nutritionLung phospholipid synthesisFat-fed animalsLung surfactant productionLavage phospholipidsGlucose-fed groupRat chowLung lavageLung tissueDietary regimensMicrosomal fatty acid elongationRat lungLung proteinFasted animalsProtein dietLungNutritional deprivationAcetyl-CoA carboxylase
1975
The Influence of Cortisol on the Enzymes of Fatty Acid Synthesis in Developing Mammalian Lung and Brain
Gross I, Rooney S, Warshaw J. The Influence of Cortisol on the Enzymes of Fatty Acid Synthesis in Developing Mammalian Lung and Brain. Pediatric Research 1975, 9: 752-755. PMID: 648, DOI: 10.1203/00006450-197509000-00014.Peer-Reviewed Original ResearchConceptsDe novo fatty acid synthesisNovo fatty acid synthesisFatty acid synthesisRabbit lungsFatty acid synthetaseAcetyl-CoA carboxylase activityAccelerated lung maturationCortisol-induced inhibitionHyaline membrane diseaseAdministration of cortisolFetal rabbit lungInfluence of cortisolFatty acid synthetase activityAcid synthesisFatty acid elongation activityAntenatal administrationNumber of inhibitoryMembrane diseaseRight lungLung maturationLung growthCortisol exposureElectron microscopic examinationFetal rabbitsFetal brainThe influence of dietary deprivation on the enzymes of fatty acid synthesis in rat brain
Gross I, Warshaw J. The influence of dietary deprivation on the enzymes of fatty acid synthesis in rat brain. Journal Of Neurochemistry 1975, 25: 191-192. PMID: 237987, DOI: 10.1111/j.1471-4159.1975.tb12251.x.Peer-Reviewed Original ResearchThe inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat
Gross I, Rooney S, Warshaw J. The inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat. Biochemical And Biophysical Research Communications 1975, 64: 59-63. PMID: 238512, DOI: 10.1016/0006-291x(75)90219-3.Peer-Reviewed Original ResearchConceptsPulmonary surfactant productionMicrosomal fatty acid elongationDietary deprivationRat lungFatty acid synthetaseDeprivation resultsAcute starvationInhibition of enzymesAcetyl-CoA carboxylaseSurfactant productionKnown inhibitionSignificant reductionFatty acid elongationFatty acidsInhibitionPhospholipid synthesisLung
1974
Enzyme Activities Related to Fatty Acid Synthesis in Developing Mammalian Lung
Gross I, Warshaw J. Enzyme Activities Related to Fatty Acid Synthesis in Developing Mammalian Lung. Pediatric Research 1974, 8: 193-199. PMID: 4150151, DOI: 10.1203/00006450-197403000-00007.Peer-Reviewed Original ResearchConceptsDe novo fatty acid synthesisNovo fatty acid synthesisFetal lifeFatty acid synthesisRabbit lungsHepatic de novo fatty acid synthesisEarly dietary intakeHepatic fatty acid synthesisFatty acidsFetal rabbit lungAcid synthesisDe novo pathwaySurface-active lipidsPulmonary synthesisFatty acid elongationLung homogenatesDietary intakeNutritional intakeFetal rabbitsMicrosomal fatty acid elongationRabbit fetusesLipid metabolismLung membranesLungAdult levelsFatty Acid Synthesis in Developing Brain
Gross I, Warshaw J. Fatty Acid Synthesis in Developing Brain. Neonatology 1974, 25: 365-375. PMID: 4156483, DOI: 10.1159/000240709.Peer-Reviewed Original ResearchMeSH KeywordsAcetyl-CoA CarboxylaseAge FactorsAnimalsAnimals, NewbornBrainFatty Acid SynthasesFatty AcidsLigasesRatsConceptsFatty acid synthesisMaximal brain growthFatty acid synthetase activityRat brainBrain supernatant fractionPostnatal lifeSupernatant fractionBrain growthAcid synthesisAdult levelsFatty acid synthetaseAcetyl-CoA carboxylase activityBrainAcetyl-CoA carboxylaseSynthetase activityFourfold differenceActivityWeeks