Stimulation of glycerolphosphate phosphatidyltransferase activity in fetal rabbit lung by cortisol administration
Rooney S, Gross I, Gassenheimer L, Motoyama E. Stimulation of glycerolphosphate phosphatidyltransferase activity in fetal rabbit lung by cortisol administration. Biochimica Et Biophysica Acta 1975, 398: 433-441. PMID: 1242106, DOI: 10.1016/0005-2760(75)90194-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCholineCytidine Diphosphate DiglyceridesEnzyme ActivationFemaleGestational AgeGlycerophosphatesHydrocortisoneLungMicroscopy, ElectronPhospholipidsPhosphotransferasesPregnancyPulmonary SurfactantsRabbitsConceptsAdministration of cortisolFetal rabbit lungLysolecithin acyltransferase activityLung maturationLiver enzymesDays gestationFetal rabbitsThyroxine treatmentGestation resultsCortisol administrationRabbit lungsCortisol treatmentDirect administrationAdministrationPulmonary surfactantSurfactant productionSignificant increaseGestationCholine phosphotransferaseAcyltransferase activityTreatmentCorticosteroidsPrevious studiesLungFetusesThe inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat
Gross I, Rooney S, Warshaw J. The inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat. Biochemical And Biophysical Research Communications 1975, 64: 59-63. PMID: 238512, DOI: 10.1016/0006-291x(75)90219-3.Peer-Reviewed Original ResearchConceptsPulmonary surfactant productionMicrosomal fatty acid elongationDietary deprivationRat lungFatty acid synthetaseDeprivation resultsAcute starvationInhibition of enzymesAcetyl-CoA carboxylaseSurfactant productionKnown inhibitionSignificant reductionFatty acid elongationFatty acidsInhibitionPhospholipid synthesisLung