1998
Fetal Lung mRNA Levels of Hox Genes Are Differentially Altered by Maternal Diabetes and Butyrate in Rats
Jacobs H, Bogue C, Pinter E, Wilson C, Warshaw J, Gross I. Fetal Lung mRNA Levels of Hox Genes Are Differentially Altered by Maternal Diabetes and Butyrate in Rats. Pediatric Research 1998, 44: 99-104. PMID: 9667378, DOI: 10.1203/00006450-199807000-00016.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsButyratesButyric AcidDiabetes Mellitus, ExperimentalEmbryonic and Fetal DevelopmentFemaleGene Expression Regulation, DevelopmentalGenes, HomeoboxGestational AgeHistone Deacetylase InhibitorsLungOrgan Culture TechniquesPregnancyPregnancy in DiabeticsRatsRats, Sprague-DawleyRNA, MessengerTranscription, GeneticConceptsLung developmentLung explantsSurfactant apoproteinExperimental animalsLung mRNA levelsElevated levelsEffect of diabetesFetal rat lung explantsLungs of fetusesRat lung explantsEffect of butyrateAntenatal exposureMaternal diabetesMetabolic abnormalitiesStreptozotocin treatmentLower incidenceNormal ratsDiabetesDexamethasoneLevel of expressionRatsTreatment of explantsSodium butyrateMRNA levelsAlters expression
1994
Butyrate modulates surfactant protein mRNA in fetal rat lung by altering mRNA transcription and stability
Peterec S, Nichols K, Dynia D, Wilson C, Gross I. Butyrate modulates surfactant protein mRNA in fetal rat lung by altering mRNA transcription and stability. American Journal Of Physiology 1994, 267: l9-l15. PMID: 8048547, DOI: 10.1152/ajplung.1994.267.1.l9.Peer-Reviewed Original ResearchConceptsFetal rat lungButyric acid analogueMRNA concentrationsRat lungNa-butyrateSP-A levelsDiabetic pregnanciesMaternal diabetesPulmonary maturationLung maturationMRNA transcriptionBiphasic effectSurfactant protein mRNAsProtein mRNASP-B mRNAAcid analoguesButyrate treatmentLungExposure of explantsFetusesInitial decreaseMRNAGene expressionButyrateMaturation
1990
Regulation of surfactant protein A mRNA by hormones and butyrate in cultured fetal rat lung
Nichols K, Floros J, Dynia D, Veletza S, Wilson C, Gross I. Regulation of surfactant protein A mRNA by hormones and butyrate in cultured fetal rat lung. American Journal Of Physiology 1990, 259: l488-l495. PMID: 2175559, DOI: 10.1152/ajplung.1990.259.6.l488.Peer-Reviewed Original Research8-Bromo Cyclic Adenosine MonophosphateAnimalsBucladesineButyratesButyric AcidDexamethasoneFetusGene Expression RegulationGlycoproteinsLungOrgan Culture TechniquesPhospholipidsProteolipidsPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated ProteinsPulmonary SurfactantsRatsRNA ProbesRNA, MessengerTriiodothyronine