2001
Is there a role for antenatal TRH therapy for the prevention of neonatal lung disease?
Gross I, Moya F. Is there a role for antenatal TRH therapy for the prevention of neonatal lung disease? Seminars In Perinatology 2001, 25: 406-416. PMID: 11778911, DOI: 10.1053/sper.2001.29032.Peer-Reviewed Original ResearchConceptsAntenatal thyrotropin-releasing hormoneThyrotropin-releasing hormoneRespiratory distress syndromeSurfactant therapyDistress syndromeOxygen dependencyAntenatal glucocorticoid treatmentLight-headed feelingPatent ductus arteriosusRetinopathy of prematurityNeonatal lung diseaseRandomized clinical trialsPituitary-thyroid axisAddition of TRHAntenatal glucocorticoidsGlucocorticoid therapyMaternal therapyNeonatal complicationsTransient complicationsTRH therapyHormone therapyBlood pressureDuctus arteriosusGlucocorticoid treatmentLung disease
1993
Combined hormonal therapy for the prevention of respiratory distress syndrome and its consequences.
Moya F, Gross I. Combined hormonal therapy for the prevention of respiratory distress syndrome and its consequences. Seminars In Perinatology 1993, 17: 267-74. PMID: 8140441.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAntenatal steroidsPostnatal surfactantSurfactant therapyPostnatal surfactant therapyRespiratory distress syndromeSteroid therapyHormonal therapyDistress syndromePremature infantsTherapyNumber of centersEnd pointRoutine useSteroidsTRHMaturation profileApparent benefitPatientsInfantsDeathTerms of RDCLDWidespread useSyndromeComparable data
1992
Plasma Thyroid Hormones and Prolactin in Premature Infants and Their Mothers after Prenatal Treatment with Thyrotropin-Releasing Hormone
Ballard P, Ballard R, Creasy R, Padbury J, Polk D, Bracken M, Moya F, Gross I. Plasma Thyroid Hormones and Prolactin in Premature Infants and Their Mothers after Prenatal Treatment with Thyrotropin-Releasing Hormone. Pediatric Research 1992, 32: 673-678. PMID: 1287557, DOI: 10.1203/00006450-199212000-00009.Peer-Reviewed Original ResearchConceptsThyroid hormonesFree thyroxineThyrotropin-releasing hormone treatmentNewborn lung diseaseDoses of TRHMU/LPituitary-thyroid functionPlasma of womenThyrotropin-Releasing HormoneWk of gestationPmol/LPlasma thyroid hormonesCord TSHTRH i.Preterm fetusesCord concentrationsControl infantsPremature infantsPostnatal surgeTRH administrationLung diseaseCord bloodPrenatal treatmentTriiodothyronine levelsHormone treatmentRespiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid
Ballard R, Ballard P, Bracken M, Moya F, Gross I, Creasy K, Padbury J, Polk D. Respiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid. The Lancet 1992, 339: 510-515. PMID: 1346877, DOI: 10.1016/0140-6736(92)90337-3.Peer-Reviewed Original ResearchMeSH KeywordsBetamethasoneChronic DiseaseDouble-Blind MethodDrug Therapy, CombinationFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Premature, DiseasesLung DiseasesMalePregnancyPrenatal CareRespiration, ArtificialRespiratory Distress Syndrome, NewbornRisk FactorsThyrotropin-Releasing HormoneConceptsChronic lung diseaseThyrotropin-releasing hormoneRespiratory distress syndromePrenatal thyrotropin-releasing hormoneDistress syndromePostconceptional ageBirthweight infantsLung diseaseSevere respiratory distress syndromeSteroid-alone groupNeonatal respiratory morbidityComplications of prematurityUnadjusted relative riskPrenatal glucocorticoid treatmentWeeks postconceptional ageTRH therapyPreterm deliveryRespiratory morbidityWeeks' gestationGlucocorticoid treatmentNeonatal periodAdverse outcomesTotal incidencePrenatal treatmentRelative risk
1988
Prevention of respiratory distress syndrome.
Moya F, Gross I. Prevention of respiratory distress syndrome. Seminars In Perinatology 1988, 12: 348-58. PMID: 3146813.Chapters
1986
Response of the Maternal, Fetal, and Neonatal Pituitary-Thyroid Axis to Thyrotropin-Releasing Hormone
Moya F, Mena P, Heusser F, Foradori A, Paiva E, Yazigi R, Michaud P, Gross I. Response of the Maternal, Fetal, and Neonatal Pituitary-Thyroid Axis to Thyrotropin-Releasing Hormone. Pediatric Research 1986, 20: 982-986. PMID: 3095783, DOI: 10.1203/00006450-198610000-00018.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFetusHumansInfant, NewbornPregnancyPrenatal Exposure Delayed EffectsProlactinThyrotropinThyrotropin-Releasing HormoneTime FactorsTriiodothyronineConceptsFetal TSHMaternal administrationPostnatal increaseElective cesarean sectionThyrotropin-Releasing HormonePituitary-thyroid axesPituitary-thyroid axisMaternal T3Maternal TSHCesarean sectionPostnatal surgePregnant womenTRH administrationPrenatal exposureFetal pituitarySignificant elevationHigh doseT3 levelsHigh dosesTRHTSHPrior exposureAdministrationNeonatesSignificant increase
1979
Thyrotropin-Releasing Hormone Increases the Amount of Surfactant in Lung Lavage from Fetal Rabbits
Rooney S, Marino P, Gobran L, Gross I, Warshaw J. Thyrotropin-Releasing Hormone Increases the Amount of Surfactant in Lung Lavage from Fetal Rabbits. Pediatric Research 1979, 13: 623-625. PMID: 112569, DOI: 10.1203/00006450-197905000-00009.Peer-Reviewed Original ResearchConceptsThyrotropin-releasing hormoneLung lavageLung maturationFetal lung slicesRespiratory distress syndromeFetal lung maturationPulmonary surfactant productionSurfactant productionPhosphatidylcholine/sphingomyelin ratioDistress syndromeTRH administrationPregnant rabbitsIncorporation of cholineFetal rabbitsGestation resultsLung slicesLavagePhysiologic roleFetusesSphingomyelin ratioTotal phospholipidsControl littersSurfactant releasePhospholipid contentMore phosphatidylcholine