2007
Circulating stem cells in extremely preterm neonates
Bizzarro MJ, Bhandari V, Krause DS, Smith BR, Gross I. Circulating stem cells in extremely preterm neonates. Acta Paediatrica 2007, 96: 521-525. PMID: 17391470, DOI: 10.1111/j.1651-2227.2007.00194.x.Peer-Reviewed Original ResearchConceptsWeeks of lifePreterm neonatesNeonatal morbidityPulmonary functionPremature neonatesGestational agePeripheral bloodInitial CD34Median gestational agePulmonary function testsShort-term outcomesUmbilical cord bloodFunction testsNeonatal demographicsBirth weightCord bloodRespiratory diseaseNeonatesCell countCD34Progenitor cellsInverse correlationWeeksBloodMorbidity
2001
Is there a role for antenatal TRH therapy for the prevention of neonatal lung disease?
Gross I, Moya F. Is there a role for antenatal TRH therapy for the prevention of neonatal lung disease? Seminars In Perinatology 2001, 25: 406-416. PMID: 11778911, DOI: 10.1053/sper.2001.29032.Peer-Reviewed Original ResearchConceptsAntenatal thyrotropin-releasing hormoneThyrotropin-releasing hormoneRespiratory distress syndromeSurfactant therapyDistress syndromeOxygen dependencyAntenatal glucocorticoid treatmentLight-headed feelingPatent ductus arteriosusRetinopathy of prematurityNeonatal lung diseaseRandomized clinical trialsPituitary-thyroid axisAddition of TRHAntenatal glucocorticoidsGlucocorticoid therapyMaternal therapyNeonatal complicationsTransient complicationsTRH therapyHormone therapyBlood pressureDuctus arteriosusGlucocorticoid treatmentLung disease
1993
Combined hormonal therapy for the prevention of respiratory distress syndrome and its consequences.
Moya F, Gross I. Combined hormonal therapy for the prevention of respiratory distress syndrome and its consequences. Seminars In Perinatology 1993, 17: 267-74. PMID: 8140441.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsDrug Therapy, CombinationEmbryonic and Fetal DevelopmentFemaleGlucocorticoidsHumansInfant, NewbornPregnancyPrenatal CareRandomized Controlled Trials as TopicRespiratory Distress Syndrome, NewbornThyroid HormonesThyrotropin-Releasing HormoneConceptsAntenatal steroidsPostnatal surfactantSurfactant therapyPostnatal surfactant therapyRespiratory distress syndromeSteroid therapyHormonal therapyDistress syndromePremature infantsTherapyNumber of centersEnd pointRoutine useSteroidsTRHMaturation profileApparent benefitPatientsInfantsDeathTerms of RDCLDWidespread useSyndromeComparable data
1992
Plasma Thyroid Hormones and Prolactin in Premature Infants and Their Mothers after Prenatal Treatment with Thyrotropin-Releasing Hormone
Ballard P, Ballard R, Creasy R, Padbury J, Polk D, Bracken M, Moya F, Gross I. Plasma Thyroid Hormones and Prolactin in Premature Infants and Their Mothers after Prenatal Treatment with Thyrotropin-Releasing Hormone. Pediatric Research 1992, 32: 673-678. PMID: 1287557, DOI: 10.1203/00006450-199212000-00009.Peer-Reviewed Original ResearchConceptsThyroid hormonesFree thyroxineThyrotropin-releasing hormone treatmentNewborn lung diseaseDoses of TRHMU/LPituitary-thyroid functionPlasma of womenThyrotropin-Releasing HormoneWk of gestationPmol/LPlasma thyroid hormonesCord TSHTRH i.Preterm fetusesCord concentrationsControl infantsPremature infantsPostnatal surgeTRH administrationLung diseaseCord bloodPrenatal treatmentTriiodothyronine levelsHormone treatmentRespiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid
Ballard R, Ballard P, Bracken M, Moya F, Gross I, Creasy K, Padbury J, Polk D. Respiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid. The Lancet 1992, 339: 510-515. PMID: 1346877, DOI: 10.1016/0140-6736(92)90337-3.Peer-Reviewed Original ResearchMeSH KeywordsBetamethasoneChronic DiseaseDouble-Blind MethodDrug Therapy, CombinationFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Premature, DiseasesLung DiseasesMalePregnancyPrenatal CareRespiration, ArtificialRespiratory Distress Syndrome, NewbornRisk FactorsThyrotropin-Releasing HormoneConceptsChronic lung diseaseThyrotropin-releasing hormoneRespiratory distress syndromePrenatal thyrotropin-releasing hormoneDistress syndromePostconceptional ageBirthweight infantsLung diseaseSevere respiratory distress syndromeSteroid-alone groupNeonatal respiratory morbidityComplications of prematurityUnadjusted relative riskPrenatal glucocorticoid treatmentWeeks postconceptional ageTRH therapyPreterm deliveryRespiratory morbidityWeeks' gestationGlucocorticoid treatmentNeonatal periodAdverse outcomesTotal incidencePrenatal treatmentRelative risk
1988
Prevention of respiratory distress syndrome.
Moya F, Gross I. Prevention of respiratory distress syndrome. Seminars In Perinatology 1988, 12: 348-58. PMID: 3146813.ChaptersMeSH KeywordsAdrenal Cortex HormonesAnimalsDrug Therapy, CombinationFemaleFetal Organ MaturityGlucocorticoidsHumansInfant, NewbornLungPregnancyRabbitsRespiratory Distress Syndrome, NewbornThyroid HormonesThyrotropin-Releasing Hormone
1987
The Biochemistry of Fetal Lung Development
Kresch M, Gross I. The Biochemistry of Fetal Lung Development. Clinics In Perinatology 1987, 14: 481-507. PMID: 3311536, DOI: 10.1016/s0095-5108(18)30747-4.ChaptersMeSH KeywordsAnimalsEmbryonic and Fetal DevelopmentHumansInfant, NewbornLungPulmonary SurfactantsRespiratory Distress Syndrome, NewbornConceptsSurfactant therapyLung complianceLung maturationAdministration of betamethasoneEffects of glucocorticoidsFetal lung developmentNumber of alveoliGlucocorticoid therapyFetal rabbitsLung developmentTherapyAnimal dataTissue complianceHormonal enhancementAdditive effectAdministrationComplianceMaturationRDSMorbidityBetamethasoneGlucocorticoidsLungMortalitySteroids
1979
Thyrotropin-Releasing Hormone Increases the Amount of Surfactant in Lung Lavage from Fetal Rabbits
Rooney S, Marino P, Gobran L, Gross I, Warshaw J. Thyrotropin-Releasing Hormone Increases the Amount of Surfactant in Lung Lavage from Fetal Rabbits. Pediatric Research 1979, 13: 623-625. PMID: 112569, DOI: 10.1203/00006450-197905000-00009.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFemaleFetusHumansInfant, NewbornLungPhosphatidylcholinesPregnancyPulmonary SurfactantsRabbitsRespiratory Distress Syndrome, NewbornSphingomyelinsTherapeutic IrrigationThyrotropin-Releasing HormoneConceptsThyrotropin-releasing hormoneLung lavageLung maturationFetal lung slicesRespiratory distress syndromeFetal lung maturationPulmonary surfactant productionSurfactant productionPhosphatidylcholine/sphingomyelin ratioDistress syndromeTRH administrationPregnant rabbitsIncorporation of cholineFetal rabbitsGestation resultsLung slicesLavagePhysiologic roleFetusesSphingomyelin ratioTotal phospholipidsControl littersSurfactant releasePhospholipid contentMore phosphatidylcholine
1976
A Comparison of Early-Onset Group B Streptococcal Neonatal Infection and the Respiratory-Distress Syndrome of the Newborn
Ablow R, Driscoll S, Effmann E, Gross I, Jolles C, Uauy R, Warshaw J. A Comparison of Early-Onset Group B Streptococcal Neonatal Infection and the Respiratory-Distress Syndrome of the Newborn. New England Journal Of Medicine 1976, 294: 65-70. PMID: 1105186, DOI: 10.1056/nejm197601082940201.Peer-Reviewed Original ResearchConceptsHyaline membrane diseaseGroup B infectionGroup B streptococcal infectionB infectionStreptococcal infectionInspiratory pressureEarly-onset group B streptococcal infectionGroup B streptococcal neonatal infectionsLower peak inspiratory pressureRespiratory distress syndromeHours of lifeLower inspiratory pressuresPeak inspiratory pressureEarly apneaNeonatal infectionNeonatal pneumoniaClinical featuresMechanical ventilationHistologic evidenceGastric aspiratesFatal casesRadiographic featuresHyaline membranesMinimal atelectasisPositive cocci