1979
Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture
Maniscalco W, Wilson C, Gross I. Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture. Pediatric Research 1979, 13: 1319-1322. PMID: 230447, DOI: 10.1203/00006450-197912000-00003.Peer-Reviewed Original ResearchConceptsFetal rat lungRat lungCyclic AMPFetal pulmonary surfactantInfluence of aminophyllineEffect of aminophyllineGlycogen synthase I activityOrgan cultureLung phospholipid synthesisGlycogen metabolismTotal phosphorylase activityDibutyryl cyclic AMPMonophosphate phosphodiesterase inhibitorSynthase I activityPhospholipid synthesisAminophyllinePhosphodiesterase inhibitorGlycogen contentLungGlycogen breakdownCyclic AMP treatmentAMP treatmentPulmonary surfactantAMPPhosphorylase activity
1977
Aminophylline stimulates the incorporation of choline into phospholipid in explants of fetal rat lung in organ culture
Gross I, Rooney S. Aminophylline stimulates the incorporation of choline into phospholipid in explants of fetal rat lung in organ culture. Biochimica Et Biophysica Acta 1977, 488: 263-269. PMID: 196659, DOI: 10.1016/0005-2760(77)90183-7.Peer-Reviewed Original ResearchConceptsFetal rat lungRat lungCholine incorporationIncorporation of cholineCyclic AMPCyclic AMP phosphodiesterase inhibitorDirect stimulatory effectOrgan cultureF12 mediumAminophylline treatmentDibutyryl cyclic AMPMM aminophyllinePhosphodiesterase inhibitorAminophyllineLungStimulatory effectSimilar changesAMPStimulationDirect effectSmall increaseCholine kinaseCholineExposurePhospholipids