2023
The impact of air pollution and endocrine disruptors on reproduction and assisted reproduction
Seli D, Taylor H. The impact of air pollution and endocrine disruptors on reproduction and assisted reproduction. Current Opinion In Obstetrics & Gynecology 2023, 35: 210-215. PMID: 36924404, DOI: 10.1097/gco.0000000000000868.Peer-Reviewed Original ResearchConceptsDiminished ovarian reserveOvarian reserveInfertility treatmentAbnormal semen parametersAssisted reproduction outcomesHuman reproductive healthEstrogen-like activityFemale reproductive functionEndocrine disruptorsPregnancy rateUterine leiomyomaReproductive healthReproduction outcomesReproductive functionSemen parametersClinical implicationsLarge-scale studiesAssisted reproductionSperm concentrationPatientsAir pollutionHealth impactsEndocrineTreatmentBisphenol A
2021
Obesity and reproduction: a committee opinion
Medicine P, Penzias A, Azziz R, Bendikson K, Falcone T, Hansen K, Hill M, Jindal S, Kalra S, Mersereau J, Reindollar R, Shannon C, Steiner A, Tanrikut C, Taylor H, Yauger B. Obesity and reproduction: a committee opinion. Fertility And Sterility 2021, 116: 1266-1285. PMID: 34583840, DOI: 10.1016/j.fertnstert.2021.08.018.Peer-Reviewed Original Research
2020
Factors associated with study protocol adherence and bio banking participation in reproductive medicine clinical trials and their relationship to live birth
Engmann L, Sun F, Legro RS, Diamond MP, Zhang H, Santoro N, Bartlebaugh C, Dodson W, Estes S, Ober J, Brzyski R, Easton C, Hernandez A, Leija M, Pierce D, Robinson R, Awonuga A, Cedo L, Cline A, Collins K, Krawetz S, Puscheck E, Singh M, Yoscovits M, Barnhart K, Coutifaris C, Lecks K, Martino L, Marunich R, Snyder P, Alvero R, Comfort A, Crow M, Schlaff W, Casson P, Hohmann A, Mallette S, Christman G, Ohl D, Ringbloom M, Tang J, Bates G, Mason S, DiMaria N, Usadi R, Lucidi R, Rhea M, Baker V, Turner K, Trussell J, DelBasso D, Huang H, Li Y, Makuch R, Patrizio P, Sakai L, Scahill L, Taylor H, Thomas T, Tsang S, Yan Q, Zhang M, Haisenleder D, Lamar C, DePaolo L, Herring A, Redmond J, Thomas M, Turek P, Wactawski-Wende J, Rebar R, Cato P, Dukic V, Lewis V, Schlegel P, Witter F. Factors associated with study protocol adherence and bio banking participation in reproductive medicine clinical trials and their relationship to live birth. Human Reproduction 2020, 35: 2819-2831. PMID: 33190149, PMCID: PMC8453415, DOI: 10.1093/humrep/deaa232.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeClinical trial protocolMedicine clinical trialsU10 HD055942U10 HD38998Baseline characteristicsTrial protocolClinical trialsLive birthsPolycystic Ovary Syndrome IIU10 HD38992U10 HD39005U10 HD27049STUDY FUNDING/COMPETINGMultiple Intrauterine GestationsStudy protocol adherenceUS multicenter trialRegular ovulatory cyclesClinical trial findingsPolycystic ovarian morphologyPARTICIPANTS/MATERIALSROLE OF CHANCELower household incomeAfrican AmericansAspects of adherence
2011
Maternal Ghrelin Deficiency Compromises Reproduction in Female Progeny through Altered Uterine Developmental Programming
Martin JR, Lieber SB, McGrath J, Shanabrough M, Horvath TL, Taylor HS. Maternal Ghrelin Deficiency Compromises Reproduction in Female Progeny through Altered Uterine Developmental Programming. Endocrinology 2011, 152: 2060-2066. PMID: 21325042, PMCID: PMC3075930, DOI: 10.1210/en.2010-1485.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEmbryo ImplantationFemaleFertilityGene Expression Regulation, DevelopmentalGhrelinHeterozygoteHomeobox A10 ProteinsHomeodomain ProteinsImmunohistochemistryLitter SizeMaleMiceMice, KnockoutProliferating Cell Nuclear AntigenReproductionReverse Transcriptase Polymerase Chain ReactionTranscription FactorsUterusWnt ProteinsConceptsGhrelin deficiencyDevelopmental programmingAbnormal endometrial functionFemale wild-type miceUterus of miceLevels of ghrelinRegulation of appetiteWild-type miceReproductive tract developmentWild-type offspringSubsequent subfertilityEndometrial proliferationUnexposed miceEndometrial functionUtero exposureUterine expressionEmbryo implantationOvarian folliclesCorpora luteaGhrelinReproductive tractTract developmentMiceSignificant alterationsSubfertility
2010
Cigarette smoke inhibits recruitment of bone-marrow-derived stem cells to the uterus
Zhou Y, Gan Y, Taylor HS. Cigarette smoke inhibits recruitment of bone-marrow-derived stem cells to the uterus. Reproductive Toxicology 2010, 31: 123-127. PMID: 20955787, PMCID: PMC3207965, DOI: 10.1016/j.reprotox.2010.10.007.Peer-Reviewed Original ResearchConceptsCigarette smoke extractStem cell recruitmentBone marrowCell recruitmentCigarette smokingLong-term organ damageHuman mesenchymal stem cellsStem cellsCigarette smoke exposureEndometrial epithelial cellsDecidualization markers prolactinBone marrow cellsMesenchymal stem cell recruitmentSmoking inhibitsOrgan damageSmoke exposureDecreased incidenceEndometrial cellsFemale infertilitySmoke extractUnfiltered cigarettesFemale C57BL/6JMouse modelCigarette smokeUterine sections
2007
Contribution of Bone Marrow‐Derived Stem Cells to Endometrium and Endometriosis
Du H, Taylor HS. Contribution of Bone Marrow‐Derived Stem Cells to Endometrium and Endometriosis. Stem Cells 2007, 25: 2082-2086. PMID: 17464086, DOI: 10.1634/stemcells.2006-0828.Peer-Reviewed Original ResearchConceptsBone marrow-derived cellsDonor-derived bone marrow cellsLacZ transgenic miceBone marrow cellsUterine endometriumBone marrowEndometrial cellsPeritoneal cavityTransgenic miceMarrow cellsStem cellsEctopic endometrial implantationNormal endometrial physiologyBone marrow-derived stem cellsBone marrow transplantationMale bone marrowMarrow-derived cellsMarrow-derived stem cellsHuman uterine endometriumEndometrial implantationMesenchymal stem cell originStem cell originMarrow transplantationEndometrial physiologyExperimental endometriosis