Risk of angioedema associated with levetiracetam compared with phenytoin: Findings of the observational health data sciences and informatics research network
Duke J, Ryan P, Suchard M, Hripcsak G, Jin P, Reich C, Schwalm M, Khoma Y, Wu Y, Xu H, Shah N, Banda J, Schuemie M. Risk of angioedema associated with levetiracetam compared with phenytoin: Findings of the observational health data sciences and informatics research network. Epilepsia 2017, 58: e101-e106. PMID: 28681416, PMCID: PMC6632067, DOI: 10.1111/epi.13828.Peer-Reviewed Original ResearchConceptsAngioedema riskAngioedema eventsHazard ratioObservational Health Data SciencesNew-user cohort studySummary hazard ratioRisk of angioedemaHealth Data SciencesAdverse event reportsPhenytoin usersResearch NetworkPhenytoin groupCohort studyTreat analysisAntiepileptic drugsComparator groupSeizure patientsLower riskLevetiracetamAngioedemaFurther studiesEvent reportsSignificant increaseRiskPhenytoin