2022
Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort
Lu Y, Van Zandt M, Liu Y, Li J, Wang X, Chen Y, Chen Z, Cho J, Dorajoo SR, Feng M, Hsu MH, Hsu JC, Iqbal U, Jonnagaddala J, Li YC, Liaw ST, Lim HS, Ngiam KY, Nguyen PA, Park RW, Pratt N, Reich C, Rhee SY, Sathappan SMK, Shin SJ, Tan HX, You SC, Zhang X, Krumholz HM, Suchard MA, Xu H. Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort. JAMA Network Open 2022, 5: e223877. PMID: 35323951, PMCID: PMC8948532, DOI: 10.1001/jamanetworkopen.2022.3877.Peer-Reviewed Original ResearchConceptsDual combination therapyUse of ACEIAntihypertensive drug classesProportion of patientsKhoo Teck Puat HospitalCombination therapyUniversity Hospital databaseHospital databaseDrug classesDual combinationSouth Western Sydney Local Health DistrictWestern Sydney Local Health DistrictPatients age 65 yearsSydney Local Health DistrictElectronic health record databasePatients age 18Local Health DistrictAge 65 yearsTreatment of hypertensionHealth record databaseARB monotherapyTreatment escalationAdult patientsCohort studyCombination regimen
2013
Opioid Use After Cardiac Surgery in Children With Down Syndrome*
Van Driest S, Shah A, Marshall M, Xu H, Smith A, McGregor T, Kannankeril J. Opioid Use After Cardiac Surgery in Children With Down Syndrome*. Pediatric Critical Care Medicine 2013, 14: 862-868. PMID: 23962833, PMCID: PMC3830692, DOI: 10.1097/pcc.0b013e31829f5d9d.Peer-Reviewed Original ResearchConceptsCardiac bypass timeCumulative opioid dosesOpioid dosesCardiac surgeryDown syndromeOpioid doseBypass timePeak serum creatinine valuesRetrospective observational comparative studyNonsteroidal anti-inflammatory drugsElectronic medical record dataAdditional operative proceduresLonger hospital staySerum creatinine valuesObservational comparative studyPediatric teaching hospitalNeuromuscular blocking agentsMedical record dataAnti-inflammatory drugsOpioid resistanceHospital stayOpioid exposureOpioid medicationsPain scoresLonger hospitalization