2021
Presence of complete murine viral genome sequences in patient-derived xenografts
Yuan Z, Fan X, Zhu J, Fu T, Wu J, Xu H, Zhang N, An Z, Zheng W. Presence of complete murine viral genome sequences in patient-derived xenografts. Nature Communications 2021, 12: 2031. PMID: 33795676, PMCID: PMC8017013, DOI: 10.1038/s41467-021-22200-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell Line, TumorGene Products, envGene Products, gagGenome, ViralHeterograftsHigh-Throughput Nucleotide SequencingHumansMiceNeoplasmsPhylogenySequence Analysis, DNAVirus DiseasesXenograft Model Antitumor AssaysConceptsPatient-derived xenograftsViral infectionMurine viral infectionHigh virus loadDrug developmentDrug metabolism-related genesVirus loadXenograft experimentsMetabolism-related genesXenograftsUnbiased data-driven approachTumor cellsInfectionExpression levelsEntire viral genomeViral genome sequencesViral sequencesViral genomeCancerImmune
2012
Genomics in 2012: challenges and opportunities in the next generation sequencing era
Zhao Z, Huang Y, Zhang B, Shyr Y, Xu H. Genomics in 2012: challenges and opportunities in the next generation sequencing era. BMC Genomics 2012, 13: s1. PMID: 23281891, PMCID: PMC3535713, DOI: 10.1186/1471-2164-13-s8-s1.Peer-Reviewed Original ResearchMeSH KeywordsComputational BiologyDatabases, FactualGenomicsHigh-Throughput Nucleotide SequencingHumansSystems BiologyConceptsNext-generation sequencing era