2023
Development of a Natural Language Processing Tool to Extract Acupuncture Point Location Terms
Li Y, Peng X, Li J, Peng S, Pei D, Tao C, Xu H, Hong N. Development of a Natural Language Processing Tool to Extract Acupuncture Point Location Terms. 2023, 00: 344-351. DOI: 10.1109/ichi57859.2023.00053.Peer-Reviewed Original ResearchAcupuncture point locationsNatural language processingRecurrent neural networkConditional random fieldWorld Health OrganizationWorld Health Organization standardsNatural language processing toolsEffect of acupuncture therapyLocation informationAcupuncture researchAcupuncture therapyAcupoint locationRecurrent neural network modelDictionary lookup methodNatural language processing modelsDeep learning techniquesAcupunctureLanguage processing toolsWestern Pacific RegionFree-text formatInternational anatomical terminologyHealth OrganizationF1 scoreInformatics applicationsNeural network
2020
Representation of EHR data for predictive modeling: a comparison between UMLS and other terminologies
Rasmy L, Tiryaki F, Zhou Y, Xiang Y, Tao C, Xu H, Zhi D. Representation of EHR data for predictive modeling: a comparison between UMLS and other terminologies. Journal Of The American Medical Informatics Association 2020, 27: 1593-1599. PMID: 32930711, PMCID: PMC7647355, DOI: 10.1093/jamia/ocaa180.Peer-Reviewed Original ResearchConceptsUnified Medical Language SystemRecurrent neural networkNeural networkPrediction performanceLogistic regressionPredictive modelingDeep learningData aggregationElectronic health record dataMachine learningRisk predictionBetter prediction performanceDengue hemorrhagic feverHealth record dataEHR dataCancer predictionLarge vocabularyDifferent tasksPredictive modelHeart failureDiabetes patientsPancreatic cancerClinical dataHemorrhagic feverICD-9Asthma Exacerbation Prediction and Risk Factor Analysis Based on a Time-Sensitive, Attentive Neural Network: Retrospective Cohort Study
Xiang Y, Ji H, Zhou Y, Li F, Du J, Rasmy L, Wu S, Zheng W, Xu H, Zhi D, Zhang Y, Tao C. Asthma Exacerbation Prediction and Risk Factor Analysis Based on a Time-Sensitive, Attentive Neural Network: Retrospective Cohort Study. Journal Of Medical Internet Research 2020, 22: e16981. PMID: 32735224, PMCID: PMC7428917, DOI: 10.2196/16981.Peer-Reviewed Original ResearchConceptsAttentive Neural NetworkAsthma exacerbationsRisk factorsNeural networkAdvanced deep learning modelsClinical variablesDeep learning modelsCerner Health Facts databaseLarge electronic health recordNeural network modelRetrospective cohort studyHealth Facts databasePotential risk factorsRisk factor analysisPersonalized risk factorsElectronic health recordsBaseline methodsLearning modelPersonalized risk scoreProgressive asthmaAsthma symptomsEsophageal refluxAdult patientsCohort studyTime-Sensitive
2019
Deep learning in clinical natural language processing: a methodical review
Wu S, Roberts K, Datta S, Du J, Ji Z, Si Y, Soni S, Wang Q, Wei Q, Xiang Y, Zhao B, Xu H. Deep learning in clinical natural language processing: a methodical review. Journal Of The American Medical Informatics Association 2019, 27: 457-470. PMID: 31794016, PMCID: PMC7025365, DOI: 10.1093/jamia/ocz200.Peer-Reviewed Original ResearchConceptsNatural language processingClinical natural language processingDeep learningLanguage processingComputing Machinery Digital LibraryInformation extraction tasksMedical informatics communityComputational Linguistics anthologyRecurrent neural networkDigital librariesText classificationElectronic health recordsExtraction taskEntity recognitionWord2vec embeddingsNeural networkRelation extractionNLP communityNLP researchInformatics communitySpecific tasksHealth recordsNLP problemLearningClinical domainsIntegrating shortest dependency path and sentence sequence into a deep learning framework for relation extraction in clinical text
Li Z, Yang Z, Shen C, Xu J, Zhang Y, Xu H. Integrating shortest dependency path and sentence sequence into a deep learning framework for relation extraction in clinical text. BMC Medical Informatics And Decision Making 2019, 19: 22. PMID: 30700301, PMCID: PMC6354333, DOI: 10.1186/s12911-019-0736-9.Peer-Reviewed Original ResearchConceptsShortest dependency pathConvolutional neural networkNeural network architectureNatural language processingSentence sequenceRelation extractionClinical relation extractionTarget entityNetwork architectureClinical textNeural networkRepresentation moduleDependency pathsDeep learning-based approachNew neural network architectureBidirectional long short-term memory networkLong short-term memory networkDeep learning frameworkDeep neural networksShort-term memory networkLearning-based approachNovel neural approachRelation extraction datasetBi-LSTM networkSyntactic features
2018
Extracting psychiatric stressors for suicide from social media using deep learning
Du J, Zhang Y, Luo J, Jia Y, Wei Q, Tao C, Xu H. Extracting psychiatric stressors for suicide from social media using deep learning. BMC Medical Informatics And Decision Making 2018, 18: 43. PMID: 30066665, PMCID: PMC6069295, DOI: 10.1186/s12911-018-0632-8.Peer-Reviewed Original ResearchConceptsConvolutional neural networkRecurrent neural networkDeep learningConditional Random FieldsSupport vector machineSuicide-related tweetsClinical textNeural networkPsychiatric stressorsExtra TreesBinary classifierTransfer learning strategiesEntity recognition taskSocial mediaExact matchTraditional machineAnnotation costLearning strategiesRecognition problemSharing flowInexact matchVector machineTwitter dataRecognition taskTwitterA study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set
Rasmy L, Wu Y, Wang N, Geng X, Zheng W, Wang F, Wu H, Xu H, Zhi D. A study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set. Journal Of Biomedical Informatics 2018, 84: 11-16. PMID: 29908902, PMCID: PMC6076336, DOI: 10.1016/j.jbi.2018.06.011.Peer-Reviewed Original ResearchConceptsRecurrent neural networkOnset riskCapability of RNNCerner Health FactsHeterogeneous EHR dataHeart failure patientsData setsElectronic health record dataDeep learning modelsDifferent patient populationsNeural network-based predictive modelDifferent patient groupsHealth record dataEHR data setsPredictive modelingSmall data setsFailure patientsPatient groupPatient populationReduction of AUCNeural networkRNN modelRETAIN modelHealth FactsHospitalClinical Named Entity Recognition Using Deep Learning Models.
Wu Y, Jiang M, Xu J, Zhi D, Xu H. Clinical Named Entity Recognition Using Deep Learning Models. AMIA Annual Symposium Proceedings 2018, 2017: 1812-1819. PMID: 29854252, PMCID: PMC5977567.Peer-Reviewed Original ResearchConceptsClinical Named Entity RecognitionNamed Entity RecognitionDeep learning modelsConvolutional neural networkClinical NER systemRecurrent neural networkNeural networkLearning modelEntity recognitionRNN modelNER systemDeep neural network architecturePopular deep learning architecturesNatural language processing tasksUnsupervised learning featuresConditional random field modelAutomatic feature learningDeep learning architectureClinical NER tasksDeep neural networksNeural network architectureClinical concept extractionLanguage processing tasksFeature learningLearning architecture
2017
Entity recognition from clinical texts via recurrent neural network
Liu Z, Yang M, Wang X, Chen Q, Tang B, Wang Z, Xu H. Entity recognition from clinical texts via recurrent neural network. BMC Medical Informatics And Decision Making 2017, 17: 67. PMID: 28699566, PMCID: PMC5506598, DOI: 10.1186/s12911-017-0468-7.Peer-Reviewed Original ResearchConceptsRecurrent neural networkNatural language processingEntity recognitionClinical textTraditional machineNeural networkClinical natural language processingMedical concept extractionHand-crafted featuresClinical entity recognitionDeep learning methodsClinical event detectionConditional Random FieldsSupport vector machineI2b2 NLP challengePerformance of LSTMTypes of entitiesClinical domainsContext informationFeature engineeringConcept extractionDe-identificationEvent detectionKnowledge basesLSTM layers
2015
Named Entity Recognition in Chinese Clinical Text Using Deep Neural Network.
Wu Y, Jiang M, Lei J, Xu H. Named Entity Recognition in Chinese Clinical Text Using Deep Neural Network. 2015, 216: 624-8. PMID: 26262126, PMCID: PMC4624324.Peer-Reviewed Original ResearchConceptsDeep neural networksLarge unlabeled corpusNamed Entity RecognitionWord embeddingsUnlabeled corpusUnsupervised learningEntity recognitionNeural networkNatural language processing technologyNovel deep learning methodLanguage processing technologyDeep learning methodsUnsupervised feature learningFeature engineering approachImportant healthcare informationChinese clinical textTypes of entitiesFeature learningNER taskClinical textLearning methodsClinical documentsCRF modelHealthcare informationFree text