2022
Risk of Developing Alzheimer’s Disease and Related Dementias in Association with Cardiovascular Disease, Stroke, Hypertension, and Diabetes in a Large Cohort of Women with Breast Cancer and with up to 26 Years of Follow-Up
Du X, Song L, Schulz P, Xu H, Chan W. Risk of Developing Alzheimer’s Disease and Related Dementias in Association with Cardiovascular Disease, Stroke, Hypertension, and Diabetes in a Large Cohort of Women with Breast Cancer and with up to 26 Years of Follow-Up. Journal Of Alzheimer's Disease 2022, 87: 415-432. PMID: 35311707, PMCID: PMC9117151, DOI: 10.3233/jad-215657.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseBreast cancerAsian/Pacific IslandersHigh riskAlzheimer's diseaseRisk of ADRDCumulative incidenceWhite womenLong-term incidencePacific IslandersBlack womenVascular diseaseHypertensionLarge cohortLower riskDiabetesRelated dementiaStrokeCancerDiseaseADRDCancer diagnosisWomenIncidenceRisk
2021
Nonselective beta‐blockers are associated with a lower risk of hepatocellular carcinoma among cirrhotic patients in the United States
Wijarnpreecha K, Li F, Xiang Y, Xu X, Zhu C, Maroufy V, Wang Q, Tao W, Dang Y, Pham H, Zhou Y, Li J, Zhang X, Xu H, Taner C, Yang L, Tao C. Nonselective beta‐blockers are associated with a lower risk of hepatocellular carcinoma among cirrhotic patients in the United States. Alimentary Pharmacology & Therapeutics 2021, 54: 481-492. PMID: 34224163, DOI: 10.1111/apt.16490.Peer-Reviewed Original ResearchConceptsRisk of HCCBeta-blocker groupHepatocellular carcinomaCirrhotic patientsCerner Health Facts databaseCox proportional hazards regressionCumulative HCC incidenceRetrospective cohort studyHealth Facts databasePopulation-based studyProportional hazards regressionKaplan-Meier estimatesEligible patientsCohort studyHCC incidenceFinal cohortHazards regressionHCC riskLower riskPropensity scorePatientsCarvedilolRiskFacts databaseGroup
2017
Risk of angioedema associated with levetiracetam compared with phenytoin: Findings of the observational health data sciences and informatics research network
Duke J, Ryan P, Suchard M, Hripcsak G, Jin P, Reich C, Schwalm M, Khoma Y, Wu Y, Xu H, Shah N, Banda J, Schuemie M. Risk of angioedema associated with levetiracetam compared with phenytoin: Findings of the observational health data sciences and informatics research network. Epilepsia 2017, 58: e101-e106. PMID: 28681416, PMCID: PMC6632067, DOI: 10.1111/epi.13828.Peer-Reviewed Original ResearchConceptsAngioedema riskAngioedema eventsHazard ratioObservational Health Data SciencesNew-user cohort studySummary hazard ratioRisk of angioedemaHealth Data SciencesAdverse event reportsPhenytoin usersResearch NetworkPhenytoin groupCohort studyTreat analysisAntiepileptic drugsComparator groupSeizure patientsLower riskLevetiracetamAngioedemaFurther studiesEvent reportsSignificant increaseRiskPhenytoin