2024
A Study of Biomedical Relation Extraction Using GPT Models.
Zhang J, Wibert M, Zhou H, Peng X, Chen Q, Keloth V, Hu Y, Zhang R, Xu H, Raja K. A Study of Biomedical Relation Extraction Using GPT Models. AMIA Joint Summits On Translational Science Proceedings 2024, 2024: 391-400. PMID: 38827097, PMCID: PMC11141827.Peer-Reviewed Original ResearchEnsemble pretrained language models to extract biomedical knowledge from literature
Li Z, Wei Q, Huang L, Li J, Hu Y, Chuang Y, He J, Das A, Keloth V, Yang Y, Diala C, Roberts K, Tao C, Jiang X, Zheng W, Xu H. Ensemble pretrained language models to extract biomedical knowledge from literature. Journal Of The American Medical Informatics Association 2024, 31: 1904-1911. PMID: 38520725, PMCID: PMC11339500, DOI: 10.1093/jamia/ocae061.Peer-Reviewed Original ResearchNatural language processingNatural language processing systemsLanguage modelExpansion of biomedical literatureZero-shot settingManually annotated corpusKnowledge graph developmentTask-specific modelsDomain-specific modelsZero-ShotEntity recognitionBillion parametersEnsemble learningLocation informationKnowledge basesBiomedical entitiesLanguage processingFree textGraph developmentBiomedical conceptsAutomated techniqueBiomedical literatureDetection methodPredictive performanceBiomedical knowledgeAdvancing entity recognition in biomedicine via instruction tuning of large language models
Keloth V, Hu Y, Xie Q, Peng X, Wang Y, Zheng A, Selek M, Raja K, Wei C, Jin Q, Lu Z, Chen Q, Xu H. Advancing entity recognition in biomedicine via instruction tuning of large language models. Bioinformatics 2024, 40: btae163. PMID: 38514400, PMCID: PMC11001490, DOI: 10.1093/bioinformatics/btae163.Peer-Reviewed Original ResearchNamed Entity RecognitionSequence labeling taskNatural language processingBiomedical NER datasetsLanguage modelNER datasetsEntity recognitionLabeling taskText generationField of natural language processingBiomedical NERFew-shot learning capabilityReasoning tasksMulti-domain scenariosDomain-specific modelsEnd-to-endMinimal fine-tuningSOTA performanceF1 scoreHealthcare applicationsBiomedical entitiesBiomedical domainLanguage processingMulti-taskingPubMedBERT model
2020
Named Entity Recognition from Table Headers in Randomized Controlled Trial Articles
Wei Q, Zhou Y, Zhao B, Hu X, Mei Q, Tao C, Xu H. Named Entity Recognition from Table Headers in Randomized Controlled Trial Articles. 2020, 00: 1-2. DOI: 10.1109/ichi48887.2020.9374323.Peer-Reviewed Original ResearchTable headersEntity recognitionDeep learning-based approachBiomedical text miningLearning-based approachNamed Entity RecognitionInformation extractionBiomedical entitiesF1 scoreText miningUnstructured natureBiomedical articlesContextual informationComputational applicationsHeaderSemantic complexityBetter performanceCorpusRecognitionInformationMiningApplicationsImportant informationComplexityBiomedical research
2017
CNN-based ranking for biomedical entity normalization
Li H, Chen Q, Tang B, Wang X, Xu H, Wang B, Huang D. CNN-based ranking for biomedical entity normalization. BMC Bioinformatics 2017, 18: 385. PMID: 28984180, PMCID: PMC5629610, DOI: 10.1186/s12859-017-1805-7.Peer-Reviewed Original ResearchConceptsBiomedical entity normalizationEntity normalizationSemantic informationCNN architectureNovel convolutional neural network architectureConvolutional neural network architectureTraditional rule-based methodsNeural network architectureRule-based systemRanking methodRule-based methodNetwork architectureBiomedical entitiesBenchmark datasetsArt performanceEntity mentionsRanking problemCNNNormalization systemArchitectureMorphological informationComparison resultsInformationDatasetSystem
2007
Gene symbol disambiguation using knowledge-based profiles
Xu H, Fan J, Hripcsak G, Mendonça E, Markatou M, Friedman C. Gene symbol disambiguation using knowledge-based profiles. Bioinformatics 2007, 23: 1015-1022. PMID: 17314123, DOI: 10.1093/bioinformatics/btm056.Peer-Reviewed Original ResearchConceptsKnowledge sourcesSimilarity scoresInformation retrieval methodsGene symbol disambiguationText mining systemKnowledge-based profilesTesting data setsBiomedical entitiesBiomedical domainMEDLINE abstractsHigh similarity scoresRetrieval methodAmbiguous genesEntrez GeneGene symbolsDisambiguation taskTesting set