2023
Cost-effectiveness of chimeric antigen receptor T-cell therapy in adults with relapsed or refractory follicular lymphoma
Potnis K, Di M, Isufi I, Gowda L, Seropian S, Foss F, Forman H, Huntington S. Cost-effectiveness of chimeric antigen receptor T-cell therapy in adults with relapsed or refractory follicular lymphoma. Blood Advances 2023, 7: 801-810. PMID: 36342852, PMCID: PMC10011202, DOI: 10.1182/bloodadvances.2022008097.Peer-Reviewed Original ResearchMeSH KeywordsAdultCell- and Tissue-Based TherapyCost-Benefit AnalysisHumansImmunotherapy, AdoptiveLymphoma, FollicularReceptors, Chimeric AntigenConceptsCAR T-cell therapyT-cell therapyQuality-adjusted life yearsIncremental cost-effectiveness ratioCAR T cellsChimeric antigen receptor T-cell therapySOC therapyFollicular lymphomaT cellsLife yearsR FLRefractory follicular lymphomaT cell strategiesThird-line settingLines of therapyIncremental clinical benefitUS payer perspectiveCost-effectiveness ratioTherapy remissionUnselected patientsCare therapyClinical benefitClinical trialsTreatment strategiesPayer perspective
2022
A systematic review of cost-effectiveness analyses on endovascular thrombectomy in ischemic stroke patients
Wu X, Khunte M, Gandhi D, Sanelli P, Forman HP, Malhotra A. A systematic review of cost-effectiveness analyses on endovascular thrombectomy in ischemic stroke patients. European Radiology 2022, 32: 3757-3766. PMID: 35301558, DOI: 10.1007/s00330-022-08671-0.Peer-Reviewed Original ResearchMeSH KeywordsCost-Benefit AnalysisHumansIschemic StrokeQuality-Adjusted Life YearsStrokeThrombectomyConceptsQuality-adjusted life yearsCost-effectiveness analysisConsolidated Health Economic Evaluation Reporting Standards (CHEERS) checklistSocietal perspectiveLife yearsIndirect costsFuture cost-effectiveness analysesLong-term horizonPay thresholdsShort-term perspectiveQALY scoresEffectiveness analysisStandard checklistCostWillingness
2020
Clinical effectiveness and cost-effectiveness of teledermatology: Where are we now, and what are the barriers to adoption?
Wang RH, Barbieri JS, Nguyen HP, Stavert R, Forman HP, Bolognia JL, Kovarik CL, Dermatology F. Clinical effectiveness and cost-effectiveness of teledermatology: Where are we now, and what are the barriers to adoption? Journal Of The American Academy Of Dermatology 2020, 83: 299-307. PMID: 32035106, PMCID: PMC7302990, DOI: 10.1016/j.jaad.2020.01.065.Peer-Reviewed Original ResearchConceptsPatient careHigh-quality dermatologic carePractice-level barriersClinical efficacyClinical effectivenessCare settingsDermatologic careCare deliveryMedicaid ServicesTeledermatology servicesTeledermatology implementationTeledermatologyCareTelemedicine reimbursementDermatologistsPotential implications
2019
Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchMeSH KeywordsAdultComputed Tomography AngiographyCost-Benefit AnalysisDisease ManagementFemaleFollow-Up StudiesHumansIntracranial AneurysmMaleMiddle AgedUnited StatesConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomesManagement of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis.
Malhotra A, Wu X, Forman HP, Matouk CC, Hughes DR, Gandhi D, Sanelli P. Management of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis. Radiology 2019, 291: 411-417. PMID: 30888931, DOI: 10.1148/radiol.2019182353.Peer-Reviewed Original ResearchMR Angiography Screening and Surveillance for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Cost-effectiveness Analysis
Malhotra A, Wu X, Matouk CC, Forman HP, Gandhi D, Sanelli P. MR Angiography Screening and Surveillance for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Cost-effectiveness Analysis. Radiology 2019, 291: 400-408. PMID: 30777807, DOI: 10.1148/radiol.2019181399.Peer-Reviewed Original Research
2018
Cost-effectiveness of Magnetic Resonance Imaging in Cervical Clearance of Obtunded Blunt Trauma After a Normal Computed Tomographic Finding
Wu X, Malhotra A, Geng B, Kalra VB, Abbed K, Forman HP, Sanelli P. Cost-effectiveness of Magnetic Resonance Imaging in Cervical Clearance of Obtunded Blunt Trauma After a Normal Computed Tomographic Finding. JAMA Surgery 2018, 153: 625-632. PMID: 29541757, PMCID: PMC5875318, DOI: 10.1001/jamasurg.2018.0099.Peer-Reviewed Original ResearchMeSH KeywordsAdultCervical VertebraeCost-Benefit AnalysisFollow-Up StudiesHumansMagnetic Resonance ImagingSpinal InjuriesTomography, X-Ray ComputedWounds, NonpenetratingConceptsMagnetic resonance imagingBlunt traumaResonance imagingCervical clearanceNeurologic deficitsTomographic findingsHealth benefitsNational Spinal Cord Injury DatabaseSpinal Cord Injury DatabaseCost of MRISpecificity of MRIUse of MRIPermanent neurologic deficitsGroup of patientsComputed tomographic findingsNegative predictive valueProbabilistic sensitivity analysesCost-effectiveness analysisLower health benefitsCervical CTCT findingsInitial CTNormal CTCervical collarCervical spine
2017
Cost-effectiveness of Magnetic Resonance Imaging in Cervical Spine Clearance of Neurologically Intact Patients With Blunt Trauma
Wu X, Malhotra A, Geng B, Liu R, Abbed K, Forman HP, Sanelli P. Cost-effectiveness of Magnetic Resonance Imaging in Cervical Spine Clearance of Neurologically Intact Patients With Blunt Trauma. Annals Of Emergency Medicine 2017, 71: 64-73. PMID: 28826754, DOI: 10.1016/j.annemergmed.2017.07.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAftercareCervical VertebraeCost-Benefit AnalysisDecision Support TechniquesHealth Care CostsHumansMagnetic Resonance ImagingMarkov ChainsModels, EconomicQuality-Adjusted Life YearsSensitivity and SpecificitySpinal InjuriesTomography, X-Ray ComputedUnited StatesWounds, NonpenetratingConceptsMagnetic resonance imagingCervical computed tomographyBlunt traumaIntact patientsUnstable injuriesCT resultsResonance imagingCost of MRICervical spine clearanceIncidence of patientsPermanent neurologic deficitsHealth benefitsNegative predictive valueProbabilistic sensitivity analysesInitial CT resultsCervical clearanceSpine clearanceNeurologic deficitsHard collarCord injuryPatient populationAlert patientsComputed tomographyPredictive valuePatients
2016
Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis
Malhotra A, Wu X, Kalra VB, Nardini HK, Liu R, Abbed KM, Forman HP. Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis. European Radiology 2016, 27: 1148-1160. PMID: 27334017, DOI: 10.1007/s00330-016-4426-z.Peer-Reviewed Original ResearchMeSH KeywordsCervical VertebraeCost-Benefit AnalysisDatabases, FactualHumansMagnetic Resonance ImagingSpinal InjuriesTomography, X-Ray ComputedWounds, NonpenetratingConceptsPositive finding rateUnstable injuriesUtility of MRIAlert patientsPooled incidenceCervical spine trauma patientsCervical spine clearanceBlunt traumatic injurySpine trauma patientsMajor medical databasesFurther studiesCS clearanceSpine clearanceTrauma patientsAwake patientsNegative CTTraumatic injuryPatientsUnique citationsSystematic reviewInjuryPositive findingsIncidenceMRIHigh false positive rateCost‐effectiveness Analysis of Follow‐up Strategies for Thunderclap Headache Patients With Negative Noncontrast CT
Malhotra A, Wu X, Kalra VB, Schindler J, Forman HP. Cost‐effectiveness Analysis of Follow‐up Strategies for Thunderclap Headache Patients With Negative Noncontrast CT. Academic Emergency Medicine 2016, 23: 243-250. PMID: 26728524, DOI: 10.1111/acem.12891.Peer-Reviewed Original ResearchCost-effectiveness analysis of CTA and LP for evaluation of suspected SAH after negative non-contrast CT
Wu X, Kalra VB, Forman HP, Malhotra A. Cost-effectiveness analysis of CTA and LP for evaluation of suspected SAH after negative non-contrast CT. Clinical Neurology And Neurosurgery 2016, 142: 104-111. PMID: 26827168, DOI: 10.1016/j.clineuro.2015.12.021.Peer-Reviewed Original Research
2015
Evaluation for Blunt Cerebrovascular Injury: Review of the Literature and a Cost-Effectiveness Analysis
Malhotra A, Wu X, Kalra VB, Schindler J, Matouk CC, Forman HP. Evaluation for Blunt Cerebrovascular Injury: Review of the Literature and a Cost-Effectiveness Analysis. American Journal Of Neuroradiology 2015, 37: 330-335. PMID: 26450540, PMCID: PMC7959958, DOI: 10.3174/ajnr.a4515.Peer-Reviewed Original ResearchConceptsCost-effective imaging strategyNet monetary benefitHealth care payer perspectiveIncremental cost-effectiveness ratioCare payer perspectiveCost-effectiveness analysisCost-effective strategyCost-effectiveness ratioEconomic evaluationMonetary benefitsDominant strategyMain indicatorsPayer perspectiveSelective DSAComparable utilityUtility perspectiveDecision tree analysisSelective anticoagulationSensitivity analysisCostImmense controversyHigh costCTA sensitivityParameter valuesHorizonScreening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis
Malhotra A, Wu X, Kalra VB, Goodman TR, Schindler J, Forman HP. Screening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis. Journal Of Pediatric Surgery 2015, 50: 1751-1757. PMID: 26546389, DOI: 10.1016/j.jpedsurg.2015.05.005.Peer-Reviewed Original ResearchMeSH KeywordsCerebral AngiographyCerebrovascular TraumaChildCost-Benefit AnalysisDecision TreesHead Injuries, ClosedHumansMonte Carlo MethodTomography, X-Ray ComputedConceptsBlunt cerebrovascular injuryPediatric blunt cerebrovascular injurySelective computed tomography angiographyComputed tomography angiographyOptimal imaging strategyCost-effectiveness analysisAnticoagulation therapyCerebrovascular injuryManagement of BCVIAppropriate anticoagulation therapyHigh-risk patientsHigh-risk factorsImaging strategiesPossible screening strategiesReview of literatureSelective anticoagulationPediatric patientsAnticoagulation complicationsTomography angiographySystematic reviewPatientsSocietal perspectiveCost-effective strategyData extractionScreening strategy
2014
Cost-Effectiveness of Angiographic Imaging in Isolated Perimesencephalic Subarachnoid Hemorrhage
Kalra VB, Wu X, Forman HP, Malhotra A. Cost-Effectiveness of Angiographic Imaging in Isolated Perimesencephalic Subarachnoid Hemorrhage. Stroke 2014, 45: 3576-3582. PMID: 25336513, DOI: 10.1161/strokeaha.114.006679.Peer-Reviewed Original ResearchMeSH KeywordsAngiography, Digital SubtractionCerebral AngiographyCost-Benefit AnalysisDecision TreesHumansMonte Carlo MethodSubarachnoid HemorrhageConceptsOptimal strategyNet monetary benefitCost-effectiveness analysisComprehensive cost-effectiveness analysisCost-effective strategyBase case scenarioDistributional variablesMonetary benefitsLife yearsWillingnessBase caseSensitivity analysisMonte Carlo simulationsInitial CTAPayCarlo simulationsPart of followCostStrategiesVariablesBenefitsDecision treeCase scenarioPurpose
2000
When is an examination complete? Lessons to be learned from cost-effectiveness analysis
Forman H. When is an examination complete? Lessons to be learned from cost-effectiveness analysis. Academic Radiology 2000, 7: 65-66. PMID: 10730160, DOI: 10.1016/s1076-6332(00)80452-3.Peer-Reviewed Original Research
1997
Health services research: the imperative revisited.
Forman H. Health services research: the imperative revisited. Radiology 1997, 203: 307-8. PMID: 9114077, DOI: 10.1148/radiology.203.2.9114077.Peer-Reviewed Original ResearchCost ControlCost-Benefit AnalysisDiffusion of InnovationHealth Services ResearchPhysiciansQuality Control
1995
Health Care Cost-Benefit and Cost-Effectiveness Analysis: An Overview
Yin D, Forman H. Health Care Cost-Benefit and Cost-Effectiveness Analysis: An Overview. Journal Of Vascular And Interventional Radiology 1995, 6: 311-320. PMID: 7647430, DOI: 10.1016/s1051-0443(95)72814-7.Peer-Reviewed Original Research
1994
Chest Radiography in Patients With Early Stage Prostatic Carcinoma Effect on Treatment Planning and Cost Analysis
Forman H, Fox L, Glazer H, McClennan B, Anderson D, Sagel S. Chest Radiography in Patients With Early Stage Prostatic Carcinoma Effect on Treatment Planning and Cost Analysis. CHEST Journal 1994, 106: 1036-1041. PMID: 7523036, DOI: 10.1378/chest.106.4.1036.Peer-Reviewed Original ResearchConceptsProstatic carcinomaChest radiographyChest radiographsRoutine preoperative chest radiographsChest radiography findingsRoutine chest radiographyRetropubic radical prostatectomyHospital-based outpatientPreoperative chest radiographProstate-specific antigenCost-effectiveness modelIntrathoracic metastasesRadiography findingsProspective studyPatient populationRadical prostatectomyClinical impactProstate carcinomaPatientsSpecific antigenPositive findingsFurther evaluationCarcinomaTreatment planningRadiographsCT screening for comorbid disease in patients with prostatic carcinoma: is it cost-effective?
Forman H, Heiken J, Brink J, Glazer H, Fox L, McClennan B. CT screening for comorbid disease in patients with prostatic carcinoma: is it cost-effective? American Journal Of Roentgenology 1994, 162: 1125-8; discussion 1129-30. PMID: 8165996, DOI: 10.2214/ajr.162.5.8165996.Peer-Reviewed Original ResearchConceptsComorbid diseasesProstatic carcinomaCT findingsFalse-positive CT findingsTime of diagnosisPopulation of patientsLack of efficacyScreening CT scanConsecutive patientsPreoperative evaluationProstatic surgeryMedical recordsClinical impactCT scanRadiation therapyPatientsCarcinomaFurther evaluationDiseaseCTMedicare reimbursementSurgeryTreatmentFindingsTherapy