2022
An unbiased kinship estimation method for genetic data analysis
Jiang W, Zhang X, Li S, Song S, Zhao H. An unbiased kinship estimation method for genetic data analysis. BMC Bioinformatics 2022, 23: 525. PMID: 36474154, PMCID: PMC9727941, DOI: 10.1186/s12859-022-05082-2.Peer-Reviewed Original ResearchConceptsRigorous mathematical proofGenetic data analysisReal data analysisUnbiased estimation methodEstimation methodIndividual-level genotype dataSample correlation coefficientMathematical proofMathematical derivationMean square errorCoefficient estimationMatrix methodEstimation accuracyEstimation biasHeritability estimationRoot mean square errorData analysisSquare errorAccurate estimatesEstimationUKINVariances of genotypesSpurious associationsKinship coefficientsEstimates
2011
Bayesian hierarchical modeling for signaling pathway inference from single cell interventional data
Luo R, Zhao H. Bayesian hierarchical modeling for signaling pathway inference from single cell interventional data. The Annals Of Applied Statistics 2011, 5: 725-745. PMID: 22162986, PMCID: PMC3233205, DOI: 10.1214/10-aoas425.Peer-Reviewed Original ResearchMarkov chain Monte CarloReal data analysisBayesian hierarchical modeling frameworkHierarchical modelingHierarchical modeling frameworkBayesian hierarchical modelingStatistical inferencePosterior distributionMonte CarloNetwork sparsitySimulation studyIntrinsic noiseModeling frameworkMeasurement errorInterventional dataInferenceMultiple protein activitiesPathway inferenceCarloModelingInterventional experimentsSuch dataSparsityData analysisNoise