Dissecting Pathway Disturbances Using Network Topology and Multi-platform Genomics Data
Zhang Y, Linder M, Shojaie A, Ouyang Z, Shen R, Baggerly K, Baladandayuthapani V, Zhao H. Dissecting Pathway Disturbances Using Network Topology and Multi-platform Genomics Data. Statistics In Biosciences 2017, 10: 86-106. PMID: 37388623, PMCID: PMC10309155, DOI: 10.1007/s12561-017-9193-0.Peer-Reviewed Original ResearchMolecular regulatory elementsCopy number variantsRegulatory elementsMRNA moleculesPathway-based analysisBRAF pathwayCancer Genome Atlas (TCGA) projectMultiple tumor lineagesTumor-specific aberrationsRegulatory topologyRelevant copy number variantsDiverse cancer typesMultiple omicsGenomic dataMajor geneCancer typesGene expressionSingle-platform analysisOncogenic pathwaysNumber variantsMethylationComplex diseasesTumor lineageAtlas projectPathway