2020
Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes
Shen LL, Ahluwalia A, Sun M, Young BK, Nardini H, Del Priore LV. Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes. British Journal Of Ophthalmology 2020, 105: 271-278. PMID: 32471821, PMCID: PMC7704705, DOI: 10.1136/bjophthalmol-2020-316028.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityLong-term natural historyHorizontal translation factorPrimary endpointVisual acuityNatural historyCommon primary endpointBCVA declineYounger patientsUntreated eyesFuture trialsTreatment trialsAge 39Transition ageSystematic reviewFunction of ageIndividual eyesChoroideremiaAgeEndpointSole endpointEyesPatientsAcuityDisease biomarkers
2019
Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data. Ophthalmology 2019, 126: 1288-1296. PMID: 31227323, DOI: 10.1016/j.ophtha.2019.05.015.Peer-Reviewed Original ResearchConceptsBaseline lesion sizeHorizontal translation factorAutosomal recessive Stargardt diseaseRecessive Stargardt diseaseLog-transformed areaLesion sizeUntreated eyesAtrophic lesionsStargardt diseaseSystematic reviewNatural historyOnset of symptomsNewcastle-Ottawa ScaleRisk of biasReliable outcome measuresIndividual-level dataAtrophy progressionFundus autofluorescenceInclusion criteriaOutcome measuresMeta-AnalysisLesion onsetProgression patternsLiterature databasesLesions
2017
Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review.
Malhotra A, Wu X, Forman HP, Grossetta Nardini HK, Matouk CC, Gandhi D, Moore C, Sanelli P. Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review. Annals Of Internal Medicine 2017, 167: 26-33. PMID: 28586893, DOI: 10.7326/m17-0246.Peer-Reviewed Original Research