2020
Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes
Shen LL, Ahluwalia A, Sun M, Young BK, Nardini H, Del Priore LV. Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes. British Journal Of Ophthalmology 2020, 105: 271-278. PMID: 32471821, PMCID: PMC7704705, DOI: 10.1136/bjophthalmol-2020-316028.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityLong-term natural historyHorizontal translation factorPrimary endpointVisual acuityNatural historyCommon primary endpointBCVA declineYounger patientsUntreated eyesFuture trialsTreatment trialsAge 39Transition ageSystematic reviewFunction of ageIndividual eyesChoroideremiaAgeEndpointSole endpointEyesPatientsAcuityDisease biomarkersTopographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis
Shen LL, Sun M, Khetpal S, Nardini H, Del Priore LV. Topographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis. Investigative Ophthalmology & Visual Science 2020, 61: 2. PMID: 31995152, PMCID: PMC7205189, DOI: 10.1167/iovs.61.1.2.Peer-Reviewed Original Research
2019
Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data. Ophthalmology 2019, 126: 1288-1296. PMID: 31227323, DOI: 10.1016/j.ophtha.2019.05.015.Peer-Reviewed Original ResearchConceptsBaseline lesion sizeHorizontal translation factorAutosomal recessive Stargardt diseaseRecessive Stargardt diseaseLog-transformed areaLesion sizeUntreated eyesAtrophic lesionsStargardt diseaseSystematic reviewNatural historyOnset of symptomsNewcastle-Ottawa ScaleRisk of biasReliable outcome measuresIndividual-level dataAtrophy progressionFundus autofluorescenceInclusion criteriaOutcome measuresMeta-AnalysisLesion onsetProgression patternsLiterature databasesLesions
2016
Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis
Malhotra A, Wu X, Kalra VB, Nardini HK, Liu R, Abbed KM, Forman HP. Utility of MRI for cervical spine clearance after blunt traumatic injury: a meta-analysis. European Radiology 2016, 27: 1148-1160. PMID: 27334017, DOI: 10.1007/s00330-016-4426-z.Peer-Reviewed Original ResearchConceptsPositive finding rateUnstable injuriesUtility of MRIAlert patientsPooled incidenceCervical spine trauma patientsCervical spine clearanceBlunt traumatic injurySpine trauma patientsMajor medical databasesFurther studiesCS clearanceSpine clearanceTrauma patientsAwake patientsNegative CTTraumatic injuryPatientsUnique citationsSystematic reviewInjuryPositive findingsIncidenceMRIHigh false positive rate