Neurometabolism in human epilepsy
Pan JW, Williamson A, Cavus I, Hetherington HP, Zaveri H, Petroff OA, Spencer DD. Neurometabolism in human epilepsy. Epilepsia 2008, 49: 31-41. PMID: 18304254, PMCID: PMC3657747, DOI: 10.1111/j.1528-1167.2008.01508.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain DiseasesBrain MappingCarbon IsotopesDominance, CerebralElectrodes, ImplantedElectroencephalographyEpilepsyGamma-Aminobutyric AcidGlucoseHippocampusHumansLimbic SystemMagnetic Resonance SpectroscopyMetabolic DiseasesMicrodialysisMitochondrial DiseasesNeural PathwaysNeuronsPositron-Emission TomographyRatsSynaptic TransmissionConceptsNeurometabolic dysfunctionMagnetic resonance spectroscopic imagingHuman epilepsyEpileptic brainHippocampal resectionSclerotic hippocampusPathophysiologic aspectsEpileptogenic processMicrodialysis measuresExtracellular glutamateEpileptic dysfunctionEnergetic dysfunctionHuman studiesDysfunctionNeurotransmitter cyclingNoninvasive functional imagingProfound decreaseMitochondrial injuryBrain functionEpilepsyFunctional imagingMetabolic imagingBrainIntracranial EEGNeurometabolism