2024
Systematic 1 Hz direct electrical stimulation for seizure induction: A reliable method for localizing seizure onset zone and predicting seizure freedom
Sivaraju A, Quraishi I, Collins E, McGrath H, Ramos A, Turk-Browne N, Zaveri H, Damisah E, Spencer D, Hirsch L. Systematic 1 Hz direct electrical stimulation for seizure induction: A reliable method for localizing seizure onset zone and predicting seizure freedom. Brain Stimulation 2024, 17: 339-345. PMID: 38490472, DOI: 10.1016/j.brs.2024.03.011.Peer-Reviewed Original ResearchSeizure inductionSeizure onset zoneSurgical outcomesHabitual seizuresOnset zonePredicting seizure freedomExcellent surgical outcomesProspective cohort studyMann-Whitney testConsecutive patientsFisher's exactSeizure freedomRefractory epilepsyCohort studyPost-surgeryInsular regionsMann-WhitneyPatientsIntracranial EEGSeizuresLocalizing seizure onset zonesStimulationElectrical stimulationMedial temporal regionsTemporal regions
2022
331 Role of Functional Network Formation in Epilepsy
Boddeti U, Bachani M, Moyer M, Owotade J, Serra R, Zaveri H, Ksendzovsky A. 331 Role of Functional Network Formation in Epilepsy. Neurosurgery 2022, 68: 75-76. DOI: 10.1227/neu.0000000000001880_331.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEpileptogenic focusFocal epilepsyTetanic stimulationGood surgical outcomePrimary mixed culturesMulti-electrode arraysCortical epilepsyRefractory seizuresSurgical resectionSurgical outcomesEpileptogenic networksVitro stimulationCortical neuronsRat pupsSeizure onsetAxonal boutonsEpilepsy patientsSurgery decisionDaily stimulationDendritic spinesSeizure formationEpilepsyVitro modelStimulationNetwork disorder
2019
The connectivity index: an effective metric for grading epileptogenicity.
Yan Q, Gaspard N, Zaveri HP, Blumenfeld H, Hirsch LJ, Spencer DD, Alkawadri R. The connectivity index: an effective metric for grading epileptogenicity. Journal Of Neurosurgery 2019, 133: 971-978. PMID: 31561212, DOI: 10.3171/2019.4.jns195.Peer-Reviewed Original ResearchSingle-pulse electrical stimulationSeizure onset zoneSite of stimulationSOZ contactsIrritative zoneComprehensive Epilepsy CenterControl contactsStimulation current intensityHabitual aurasHabitual seizuresEpilepsy centersSeizure generationBrain sitesFrequency stimulationEpileptic activityElectrical stimulationOnset zonePatientsRecording contactsStimulation sessionsBrain regionsFunctional connectivityStimulationOutcome casesSeizures
2008
Local spatial effect of 50 Hz cortical stimulation in humans
Gwinn RP, Spencer DD, Spencer SS, Duckrow RB, Vives K, Wu K, Tkeshelashvili D, Zaveri HP. Local spatial effect of 50 Hz cortical stimulation in humans. Epilepsia 2008, 49: 1602-1610. PMID: 18435750, DOI: 10.1111/j.1528-1167.2008.01628.x.Peer-Reviewed Original ResearchConceptsCortical stimulationStimulation amplitudeBipolar stimulationFunctional cortical mappingSeizure activityFunctional mapping proceduresCortical mappingEfficacious treatmentSubdural electrodesCortical activityStimulation parametersHuman investigationsStimulating parametersStimulationTissue volumeElectrode placementCortical surfacePatientsGreater increaseBaselineFunctional mappingGamma bandBand powerStimuliS poststimulation