2000
Comparison of the percent free prostate-specific antigen levels in the serum of healthy men and in men with recurrent prostate cancer after radical prostatectomy
Scorilas A, Yu H, Soosaipillai A, Gregorakis A, Diamandis E. Comparison of the percent free prostate-specific antigen levels in the serum of healthy men and in men with recurrent prostate cancer after radical prostatectomy. Clinica Chimica Acta 2000, 292: 127-138. PMID: 10686282, DOI: 10.1016/s0009-8981(99)00211-9.Peer-Reviewed Original ResearchConceptsPercent free PSAProstate cancer patientsFree PSAProstate cancerCancer patientsRadical prostatectomyPercent free prostate-specific antigen levelsCancer aggressivenessFree prostate specific antigen levelsProstate-specific antigen levelProstate cancer screening programsAge-matched menCancer screening programsRecurrent prostate cancerBenign prostatic hyperplasiaProstate cancer aggressivenessAntigen levelsTotal PSAGleason scoreHealthy menProstatic hyperplasiaProstatic diseaseScreening programPatientsPathological indicators
1999
Insulin‐like growth factors (IGF‐I, free IGF‐I, and IGF‐II) and insulin‐like growth factor binding proteins (IGFBP‐2, IGFBP‐3, IGFBP‐6, and ALS) in blood circulation
Yu H, Mistry J, Nicar M, Khosravi M, Diamandis A, van Doorn J, Juul A. Insulin‐like growth factors (IGF‐I, free IGF‐I, and IGF‐II) and insulin‐like growth factor binding proteins (IGFBP‐2, IGFBP‐3, IGFBP‐6, and ALS) in blood circulation. Journal Of Clinical Laboratory Analysis 1999, 13: 166-172. PMID: 10414596, PMCID: PMC6808158, DOI: 10.1002/(sici)1098-2825(1999)13:4<166::aid-jcla5>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood CirculationBlood ProteinsCarrier ProteinsFemaleGlycoproteinsHumansImmunoassayInsulin-Like Growth Factor Binding Protein 2Insulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding Protein 6Insulin-Like Growth Factor IInsulin-Like Growth Factor IIMaleMiddle AgedProtein BindingReceptors, SomatomedinReference ValuesSomatomedinsConceptsInsulin-like growth factorTotal insulin-like growth factorIGF-II levelsIGFBP-3IGFBP-6Growth factorLevels of IGFFree insulin-like growth factorIGFBP-2 levelsIGFBP-2Plasma levelsEpidemiological studiesReference rangeNormal populationPubertyBlood circulationAgeSerumBirthCell growthALSMalesFemalesSimilar patternGender
1996
Ultrasensitive prostate-specific antigen assays and their clinical application.
Diamandis E, Yu H, Melegos D. Ultrasensitive prostate-specific antigen assays and their clinical application. Clinical Chemistry 1996, 42: 853-857. PMID: 8665675, DOI: 10.1093/clinchem/42.6.853.Peer-Reviewed Original ResearchUltrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite immunochemiluminescent third-generation assay: potential applications in prostate and breast cancers.
Ferguson R, Yu H, Kalyvas M, Zammit S, Diamandis E. Ultrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite immunochemiluminescent third-generation assay: potential applications in prostate and breast cancers. Clinical Chemistry 1996, 42: 675-684. PMID: 8653891, DOI: 10.1093/clinchem/42.5.675.Peer-Reviewed Original ResearchConceptsTime-resolved immunofluorometric assayProstate-specific antigenL PSAPotential applicationsUltrasensitive time-resolved immunofluorometric assayUltrasensitive detectionPSA immunoreactivityImmunofluorometric assayWide dynamic rangeFree prostate-specific antigenPostradical prostatectomy patientsEstrogen receptor positivityUltrasensitive PSA assaysDynamic rangePSA changeReceptor positivityProstatectomy patientsProstate cancerBreast cancerPSA assaysHook effectLow analytical limitsSignificant associationMonoclonal antibodiesSerum samplesAssay of prostate-specific antigen from whole blood spotted on filter paper and application to prostate cancer screening.
Hoffman B, Yu H, Diamandis E. Assay of prostate-specific antigen from whole blood spotted on filter paper and application to prostate cancer screening. Clinical Chemistry 1996, 42: 536-544. PMID: 8605670, DOI: 10.1093/clinchem/42.4.536.Peer-Reviewed Original ResearchConceptsProstate-specific antigenProstate cancerOccult prostate cancerWhole bloodWhole blood concentrationsExtracts of bloodFilter paper procedureMicrograms/L.Cancer screeningPSA recoverySy/xBloodPlasma fractionConcentration of PSARegression analysisCancerAntigenCentralized laboratoriesMicroL of bufferMicroLFilter paperPaper discsHematocritRecoveryMonths