1996
Prostate specific antigen — a new constituent of breast cyst fluid
Diamandis E, Yu H, López-Otín C. Prostate specific antigen — a new constituent of breast cyst fluid. Breast Cancer Research And Treatment 1996, 38: 259-264. PMID: 8739078, DOI: 10.1007/bf01806144.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlotting, WesternChromatography, High Pressure LiquidExudates and TransudatesFemaleFibrocystic Breast DiseaseHumansProstate-Specific AntigenConceptsProstate-specific antigenBreast cyst fluidCyst fluidSpecific antigenFree prostate-specific antigenBreast cystic diseasePSA presenceWestern blot analysisCystic diseaseBreast cancerNormal breastCutoff levelΑ1-antichymotrypsinMore studiesBlot analysisHigh-performance liquid chromatographyAntigenFrequent componentPerformance liquid chromatographySerine proteasesLiquid chromatographyCancerBreastDisease
1995
Prostate-specific antigen in serum of women with breast cancer
Giai M, Yu H, Roagna R, Ponzone R, Katsaros D, Levesque M, Diamandis E. Prostate-specific antigen in serum of women with breast cancer. British Journal Of Cancer 1995, 72: 728-731. PMID: 7545417, PMCID: PMC2033864, DOI: 10.1038/bjc.1995.401.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsChromatography, High Pressure LiquidCytosolFemaleHumansMiddle AgedPostoperative PeriodProstate-Specific AntigenReference ValuesConceptsSerum prostate-specific antigenProstate-specific antigenBreast cancer patientsBreast cancerPSA levelsCancer patientsTumor cytosolsBreast tumorsPSA concentrationFree prostate-specific antigenSerum of womenFavorable prognostic indicatorSerum PSA levelsNormal male serumFemale breast tumorsBreast cancer diagnosisPresurgical seraPrognostic indicatorSurgical removalNormal breastMale serumCancerSerumCancer diagnosisTumorsQuantification of creatine kinase BB isoenzyme in tumor cytosols and serum with an ultrasensitive time-resolved immunofluorometric technique
Zarghami N, Yu H, Diamandis E, Sutherland D. Quantification of creatine kinase BB isoenzyme in tumor cytosols and serum with an ultrasensitive time-resolved immunofluorometric technique. Clinical Biochemistry 1995, 28: 243-253. PMID: 7554242, DOI: 10.1016/0009-9120(95)00010-7.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBreast NeoplasmsChromatography, High Pressure LiquidCreatine KinaseCytosolFemaleFluoroimmunoassayHumansIsoenzymesMaleProstatic NeoplasmsReceptors, EstrogenSensitivity and SpecificityConceptsCK-BB levelsBreast tumor cytosolsCreatine kinase BBCK-BBProstate cancerTumor cytosolsCancer patientsEstrogen sensitivityHealthy subjectsSerum CK-BB levelsActive prostate cancerSensitive immunofluorometric procedurePost-radical prostatectomyProstate cancer patientsSerum CK-BBCK-BB isoenzymeSteroid hormone receptorsSerum PSAProgesterone receptorRadical prostatectomyBreast cancerMale volunteersHealthy volunteersPatientsBreast tumorsExpression of the prostate-specific antigen gene by a primary ovarian carcinoma.
Yu H, Diamandis E, Levesque M, Asa S, Monne M, Croce C. Expression of the prostate-specific antigen gene by a primary ovarian carcinoma. Cancer Research 1995, 55: 1603-6. PMID: 7536128.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBlotting, SouthernBudd-Chiari SyndromeChromatography, High Pressure LiquidDNA PrimersDNA, NeoplasmFemaleGene ExpressionGlucocorticoidsHumansImmunohistochemistryLiver TransplantationMiddle AgedMolecular Sequence DataOvarian NeoplasmsPolymerase Chain ReactionProstate-Specific AntigenConceptsProstate-specific antigenPrimary ovarian carcinomasLiver transplantationOvarian tumorsOvarian carcinomaPSA geneProstate-specific antigen geneBreast carcinoma cell linesCarcinoma cell linesPSA cDNAProstate tissueTumor tissueTumorsEpithelial cellsTranscription-PCRWhole coding sequencePatientsTransplantationCarcinomaCell linesImmunohistochemistryAntigen geneTissue culture experimentsTissueDNA sequencingProstate-specific antigen immunoreactivity in amniotic fluid.
Yu H, Diamandis E. Prostate-specific antigen immunoreactivity in amniotic fluid. Clinical Chemistry 1995, 41: 204-210. PMID: 7533063, DOI: 10.1093/clinchem/41.2.204.Peer-Reviewed Original ResearchMeSH KeywordsAlpha 1-AntichymotrypsinAlpha-FetoproteinsAmniotic FluidChromatography, High Pressure LiquidFemaleFetal BloodFluoroimmunoassayGestational AgeHumansMaternal AgePregnancyProstate-Specific AntigenReference ValuesConceptsProtease prostate-specific antigenAmniotic fluidAlpha-fetoproteinGestational ageProstate-specific antigen immunoreactivitySensitive immunofluorometric procedureHigh alpha-fetoproteinHigher PSA concentrationsProstate-specific antigenNormal fetal developmentGrowth factor regulatorSerine protease prostate-specific antigenNonpregnant womenMaternal serumPregnant womenAntigen immunoreactivityBreast tumorsFetal developmentPSA concentrationImmunofluorometric procedurePregnancySignificant correlationWomenAgeSyndromeImmunoreactive prostate‐specific antigen in lung tumors
Levesque M, Yu H, D'Costa M, Tadross L, Diamandis E. Immunoreactive prostate‐specific antigen in lung tumors. Journal Of Clinical Laboratory Analysis 1995, 9: 375-379. PMID: 8587005, DOI: 10.1002/jcla.1860090607.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaCarcinoma, Squamous CellChromatography, High Pressure LiquidFemaleHumansImmunohistochemistryLung NeoplasmsMaleMolecular WeightPrognosisProstate-Specific AntigenConceptsProstate-specific antigenImmunoreactive prostate-specific antigenLung tumor extractsFavorable prognostic indicatorSquamous cell carcinomaSteroid hormone actionMale patientsPrognostic significanceCell carcinomaPrognostic indicatorLung cancerLung tissueBreast cancerLung tumorsPresence of PSAProstate carcinomaTumor extractsBreast tumorsBiochemical markersHormone actionTumorsEpithelial cellsCarcinomaCancerAntigenProstate-specific antigen in milk of lactating women.
Yu H, Diamandis E. Prostate-specific antigen in milk of lactating women. Clinical Chemistry 1995, 41: 54-58. PMID: 7529146, DOI: 10.1093/clinchem/41.1.54.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlotting, WesternChromatography, High Pressure LiquidFemaleHumansLactationMaleMilk, HumanMolecular WeightProstate-Specific AntigenRegression AnalysisTime FactorsConceptsProstate-specific antigenBreast milkPSA concentrationTotal prostate-specific antigenCancerous prostatic tissueMicrograms/LConditions of stimulationWestern blot analysisWeeks postdeliveryPresence of PSANormal breastProstatic tissueAmniotic fluidMother's ageBreast tumorsFemale breastSteroid hormonesPSA-alphaSensitive prostate specific antigenGrowth factorSpecific markersPostdeliveryBlot analysisBreastAntigen
1994
Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines
Yu H, Diamandis E, Zarghami N, Grass L. Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines. Breast Cancer Research And Treatment 1994, 32: 291-300. PMID: 7532467, DOI: 10.1007/bf00666006.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, WesternBreast NeoplasmsChromatography, High Pressure LiquidEstradiolEstroneHumansProstate-Specific AntigenSteroidsTamoxifenTestosteroneTumor Cells, CulturedConceptsProstate-specific antigenProstate-specific antigen (PSA) productionSpecific antigen productionBreast cancer cell linesCell linesCell line TCancer cell linesPSA productionNew therapiesSpecific antigenBreast tumorsT-47DAntigen productionSuch stimulationMCF-7AndrogensPrevious reportsInductionGlucocorticosteroidsMineralocorticosteroidsData supportProgestinsPrognosisTamoxifenAntiestrogens
1993
Ultrasensitive time-resolved immunofluorometric assay of prostate-specific antigen in serum and preliminary clinical studies.
Yu H, Diamandis E. Ultrasensitive time-resolved immunofluorometric assay of prostate-specific antigen in serum and preliminary clinical studies. Clinical Chemistry 1993, 39: 2108-2114. PMID: 7691442, DOI: 10.1093/clinchem/39.10.2108.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlkaline PhosphataseAntibodies, MonoclonalChromatography, High Pressure LiquidEdetic AcidFemaleFluoroimmunoassayHumansMaleMiddle AgedNeoplasm Recurrence, LocalProstatectomyProstate-Specific AntigenProstatic NeoplasmsQuality ControlReference ValuesSensitivity and SpecificityTerbiumConceptsL PSAPolyclonal detection antibodyUltrasensitive time-resolved immunofluorometric assaySensitive prostate specific antigenPSA antibodyDetection antibodyTime-resolved fluorometryTime-resolved immunofluorometric assayUltrasensitive methodProstate-specific antigenMicrotiter wellsImmunofluorometric assayClinical applicationStreptavidinExtreme sensitivityAssays