D-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer
Yu X, Lin H, Wang Y, Lv W, Zhang S, Qian Y, Deng X, Feng N, Yu H, Qian B. D-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer. OncoTargets And Therapy 2018, 11: 1833-1847. PMID: 29670359, PMCID: PMC5894671, DOI: 10.2147/ott.s155716.Peer-Reviewed Original ResearchLung cancer cellsLung cancerCancer cellsTherapeutic effectUse of chloroquineXenograft animal modelCell Counting Kit-8Real-time quantitative polymerase chain reactionCounting Kit-8Flow cytometric analysisQuantitative polymerase chain reactionMechanism of actionExpression of apoptosisPolymerase chain reactionApoptosis-related gene expressionAnimal modelsNude miceCytometric analysisKit-8Western blotAutophagy markersAutophagy inhibitorCancerAntitumor activityProapoptotic effects